Serum Predose Metabolic Profiling for Prediction of Rosuvastatin Pharmacokinetic Parameters in Healthy Volunteers
Rosuvastatin is a well-known lipid-lowering agent generally used for hypercholesterolemia treatment and coronary artery disease prevention. There is a substantial inter-individual variability in the absorption of statins usually caused by genetic polymorphisms leading to a variation in the correspon...
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Autores principales: | Anne Michelli Reis Silveira, Gustavo Henrique Bueno Duarte, Anna Maria Alves de Piloto Fernandes, Pedro Henrique Dias Garcia, Nelson Rogerio Vieira, Marcia Aparecida Antonio, Patricia de Oliveira Carvalho |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/ee722c3b6d8b41b6b7a2d30a17918c5e |
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