Oral Hsp90 inhibitor SNX-5422 attenuates SARS-CoV-2 replication and dampens inflammation in airway cells

Summary: Currently available SARS-CoV-2 therapeutics are targeted toward moderately to severely ill patients and require intravenous infusions, with limited options for exposed or infected patients with no or mild symptoms. Although vaccines have demonstrated protective efficacy, vaccine hesitancy a...

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Autores principales: Ria Goswami, Veronica S. Russell, Joshua J. Tu, Charlene Thomas, Philip Hughes, Francine Kelly, Stephanie N. Langel, Justin Steppe, Scott M. Palmer, Timothy Haystead, Maria Blasi, Sallie R. Permar
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/ee780399eaa745259751f63b2147a779
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