Comparison of the gene expression profiles of human fetal cortical astrocytes with pluripotent stem cell derived neural stem cells identifies human astrocyte markers and signaling pathways and transcription factors active in human astrocytes.
Astrocytes are the most abundant cell type in the central nervous system (CNS) and have a multitude of functions that include maintenance of CNS homeostasis, trophic support of neurons, detoxification, and immune surveillance. It has only recently been appreciated that astrocyte dysfunction is a pri...
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Auteurs principaux: | Nasir Malik, Xiantao Wang, Sonia Shah, Anastasia G Efthymiou, Bin Yan, Sabrina Heman-Ackah, Ming Zhan, Mahendra Rao |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2014
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Sujets: | |
Accès en ligne: | https://doaj.org/article/ee7c380eedef486580b14bf3ce02f19f |
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