A family of unconventional deubiquitinases with modular chain specificity determinants

Deubiquitinating enzymes (DUBs) are essential to modulate ubiquitin signaling. While known DUBs can be grouped into six families, the authors here present biochemical and structural evidence for a seventh DUB family, defining determinants of substrate specificity for two representative enzymes.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Thomas Hermanns, Christian Pichlo, Ilka Woiwode, Karsten Klopffleisch, Katharina F. Witting, Huib Ovaa, Ulrich Baumann, Kay Hofmann
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/ee7d765deef64ba6a8f81356743f0721
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires