Influence of thyrotropic herbal remedy on vascular endothelium and thyroid gland structure in experimental hypothyroidism

The work presents evaluation of influence of plant preparation «Thyreoton-forte» on endothelium of vessels and morphological structure of thyroid gland in experimental hypothyreosis. Experimental hypothyreosis in rats was induced by administration of mercazolilum (10 mg/kg, intragastric introduction...

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Main Authors: S. M. Gulyayev, E. V. Arkhipova, S. V. Lemza, N. A. Khamayeva, S. M. Nikolayev
Format: article
Language:RU
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2014
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Online Access:https://doaj.org/article/ee8fd471b3e0429b94669a40c12a4745
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Summary:The work presents evaluation of influence of plant preparation «Thyreoton-forte» on endothelium of vessels and morphological structure of thyroid gland in experimental hypothyreosis. Experimental hypothyreosis in rats was induced by administration of mercazolilum (10 mg/kg, intragastric introduction) during 28 days. The course administration of «Thyreoton-forte» (50,100 mg/kg, intragastric introduction) decreases the number of circulating endothelial cells (p < 0,05) and normalizes the structure of thyroid gland. Pharmacological effect of «Thyreoton-forte» is provided by protective influence in vascular endothelium and positive action on thyroid gland.