Estimating diarrhea mortality among young children in low and middle income countries.

<h4>Background</h4>Diarrhea remains one of the leading causes of morbidity and mortality among children under 5 years of age, but in many low and middle-income countries where vital registration data are lacking, updated estimates with regard to the proportion of deaths attributable to d...

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Autores principales:	Christa L Fischer Walker, Martin J Aryee, Cynthia Boschi-Pinto, Robert E Black
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ee99b0a86133497b8343c44afbe7a055
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spelling	oai:doaj.org-article:ee99b0a86133497b8343c44afbe7a0552021-11-18T07:31:10ZEstimating diarrhea mortality among young children in low and middle income countries.1932-620310.1371/journal.pone.0029151https://doaj.org/article/ee99b0a86133497b8343c44afbe7a0552012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22235266/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Diarrhea remains one of the leading causes of morbidity and mortality among children under 5 years of age, but in many low and middle-income countries where vital registration data are lacking, updated estimates with regard to the proportion of deaths attributable to diarrhea are needed.<h4>Methods</h4>We conducted a systematic literature review to identify studies reporting diarrhea proportionate mortality for children 1-59 mo of age published between 1980 and 2009. Using the published proportionate mortality estimates and country level covariates we constructed a logistic regression model to estimate country and regional level proportionate mortality and estimated uncertainty bounds using Monte-Carlo simulations.<h4>Findings</h4>We identified more than 90 verbal autopsy studies from around the world to contribute data to a single-cause model. We estimated diarrhea proportionate mortality for 84 countries in 6 regions and found diarrhea to account for between 10.0% of deaths in the Americas to 31.3% of deaths in the South-east Asian region.<h4>Discussion</h4>Diarrhea remains a leading cause of death for children 1-59 mo of age. Published literature can be used to create a single-cause mortality disease model to estimate mortality for countries lacking vital registration data.Christa L Fischer WalkerMartin J AryeeCynthia Boschi-PintoRobert E BlackPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 1, p e29151 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Christa L Fischer Walker Martin J Aryee Cynthia Boschi-Pinto Robert E Black Estimating diarrhea mortality among young children in low and middle income countries.
description	<h4>Background</h4>Diarrhea remains one of the leading causes of morbidity and mortality among children under 5 years of age, but in many low and middle-income countries where vital registration data are lacking, updated estimates with regard to the proportion of deaths attributable to diarrhea are needed.<h4>Methods</h4>We conducted a systematic literature review to identify studies reporting diarrhea proportionate mortality for children 1-59 mo of age published between 1980 and 2009. Using the published proportionate mortality estimates and country level covariates we constructed a logistic regression model to estimate country and regional level proportionate mortality and estimated uncertainty bounds using Monte-Carlo simulations.<h4>Findings</h4>We identified more than 90 verbal autopsy studies from around the world to contribute data to a single-cause model. We estimated diarrhea proportionate mortality for 84 countries in 6 regions and found diarrhea to account for between 10.0% of deaths in the Americas to 31.3% of deaths in the South-east Asian region.<h4>Discussion</h4>Diarrhea remains a leading cause of death for children 1-59 mo of age. Published literature can be used to create a single-cause mortality disease model to estimate mortality for countries lacking vital registration data.
format	article
author	Christa L Fischer Walker Martin J Aryee Cynthia Boschi-Pinto Robert E Black
author_facet	Christa L Fischer Walker Martin J Aryee Cynthia Boschi-Pinto Robert E Black
author_sort	Christa L Fischer Walker
title	Estimating diarrhea mortality among young children in low and middle income countries.
title_short	Estimating diarrhea mortality among young children in low and middle income countries.
title_full	Estimating diarrhea mortality among young children in low and middle income countries.
title_fullStr	Estimating diarrhea mortality among young children in low and middle income countries.
title_full_unstemmed	Estimating diarrhea mortality among young children in low and middle income countries.
title_sort	estimating diarrhea mortality among young children in low and middle income countries.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/ee99b0a86133497b8343c44afbe7a055
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Estimating diarrhea mortality among young children in low and middle income countries.

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