In-hospital mortality among consecutive patients with ST-Elevation myocardial infarction in modern primary percutaneous intervention era ~ Insights from 15-year data of single-center hospital-based registry ~.
<h4>Objective</h4>To clarify the association of detailed angiographic findings with in-hospital outcome after primary percutaneous coronary intervention (p-PCI) for ST-elevation myocardial infarction (STEMI) in Japan.<h4>Background</h4>Data regarding the association of detail...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/ee9bfe9f43f547c590434186927b8d6a |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:ee9bfe9f43f547c590434186927b8d6a |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:ee9bfe9f43f547c590434186927b8d6a2021-12-02T20:07:09ZIn-hospital mortality among consecutive patients with ST-Elevation myocardial infarction in modern primary percutaneous intervention era ~ Insights from 15-year data of single-center hospital-based registry ~.1932-620310.1371/journal.pone.0252503https://doaj.org/article/ee9bfe9f43f547c590434186927b8d6a2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0252503https://doaj.org/toc/1932-6203<h4>Objective</h4>To clarify the association of detailed angiographic findings with in-hospital outcome after primary percutaneous coronary intervention (p-PCI) for ST-elevation myocardial infarction (STEMI) in Japan.<h4>Background</h4>Data regarding the association of detailed angiographic findings with in-hospital outcome after STEMI are limited in the p-PCI era.<h4>Methods</h4>Between January-2004 and December-2018, 1735 patients with STEMI (mean age, 68.5 years; female, 24.6%) who presented to the hospital in the 24-hours after symptom onset and underwent p-PCI were evaluated using the disease registries. The registry is an ongoing, retrospective, single-center hospital-based registry.<h4>Results</h4>The 30-day mortality rate and in-hospital mortality rate were 7.7% and 9.2%, respectively. Independent predictors of in-hospital mortality were ejection fraction (EF) < 40% [adjusted Odds Ratio (aOR), 4.446, p < 0.001], culprit lesions in the left coronary artery (LCA) (aOR, 2.940, p < 0.001) compared with those in the right coronary artery, Killip class > II (aOR, 7.438; p < 0.001), chronic kidney disease (CKD) (aOR, 4.056; p < 0.001), final thrombolysis in myocardial infarction (TIMI) grades 0/1/2 (aOR, 1.809; p = 0.03), absence of robust collaterals (aOR, 17.309; p = 0.01) and hypertension (aOR, 0.449; p = 0.01).<h4>Conclusions</h4>Among the consecutive patients with STEMI, the in-hospital mortality rate after p-PCI significantly improved in the second half. Not only CKD, Killip class > II, and EF < 40%, but also the angiographic findings such as culprit lesions in the LCA, absence of very robust collaterals, and final TIMI grades <3 were associated with an increased risk of in-hospital mortality.Kensuke TakagiAkihito TanakaNaoki YoshiokaYasuhiro MoritaRuka YoshidaYasunori KanzakiNaoki WatanabeRyota YamauchiShotaro KomeyamaHiroki SugiyamaKazuki ShimojoTakuro ImaokaGaku SakamotoTakuma OhiHiroki GotoHideki IshiiItsuro MorishimaToyoaki MuroharaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0252503 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Kensuke Takagi Akihito Tanaka Naoki Yoshioka Yasuhiro Morita Ruka Yoshida Yasunori Kanzaki Naoki Watanabe Ryota Yamauchi Shotaro Komeyama Hiroki Sugiyama Kazuki Shimojo Takuro Imaoka Gaku Sakamoto Takuma Ohi Hiroki Goto Hideki Ishii Itsuro Morishima Toyoaki Murohara In-hospital mortality among consecutive patients with ST-Elevation myocardial infarction in modern primary percutaneous intervention era ~ Insights from 15-year data of single-center hospital-based registry ~. |
| description |
<h4>Objective</h4>To clarify the association of detailed angiographic findings with in-hospital outcome after primary percutaneous coronary intervention (p-PCI) for ST-elevation myocardial infarction (STEMI) in Japan.<h4>Background</h4>Data regarding the association of detailed angiographic findings with in-hospital outcome after STEMI are limited in the p-PCI era.<h4>Methods</h4>Between January-2004 and December-2018, 1735 patients with STEMI (mean age, 68.5 years; female, 24.6%) who presented to the hospital in the 24-hours after symptom onset and underwent p-PCI were evaluated using the disease registries. The registry is an ongoing, retrospective, single-center hospital-based registry.<h4>Results</h4>The 30-day mortality rate and in-hospital mortality rate were 7.7% and 9.2%, respectively. Independent predictors of in-hospital mortality were ejection fraction (EF) < 40% [adjusted Odds Ratio (aOR), 4.446, p < 0.001], culprit lesions in the left coronary artery (LCA) (aOR, 2.940, p < 0.001) compared with those in the right coronary artery, Killip class > II (aOR, 7.438; p < 0.001), chronic kidney disease (CKD) (aOR, 4.056; p < 0.001), final thrombolysis in myocardial infarction (TIMI) grades 0/1/2 (aOR, 1.809; p = 0.03), absence of robust collaterals (aOR, 17.309; p = 0.01) and hypertension (aOR, 0.449; p = 0.01).<h4>Conclusions</h4>Among the consecutive patients with STEMI, the in-hospital mortality rate after p-PCI significantly improved in the second half. Not only CKD, Killip class > II, and EF < 40%, but also the angiographic findings such as culprit lesions in the LCA, absence of very robust collaterals, and final TIMI grades <3 were associated with an increased risk of in-hospital mortality. |
| format |
article |
| author |
Kensuke Takagi Akihito Tanaka Naoki Yoshioka Yasuhiro Morita Ruka Yoshida Yasunori Kanzaki Naoki Watanabe Ryota Yamauchi Shotaro Komeyama Hiroki Sugiyama Kazuki Shimojo Takuro Imaoka Gaku Sakamoto Takuma Ohi Hiroki Goto Hideki Ishii Itsuro Morishima Toyoaki Murohara |
| author_facet |
Kensuke Takagi Akihito Tanaka Naoki Yoshioka Yasuhiro Morita Ruka Yoshida Yasunori Kanzaki Naoki Watanabe Ryota Yamauchi Shotaro Komeyama Hiroki Sugiyama Kazuki Shimojo Takuro Imaoka Gaku Sakamoto Takuma Ohi Hiroki Goto Hideki Ishii Itsuro Morishima Toyoaki Murohara |
| author_sort |
Kensuke Takagi |
| title |
In-hospital mortality among consecutive patients with ST-Elevation myocardial infarction in modern primary percutaneous intervention era ~ Insights from 15-year data of single-center hospital-based registry ~. |
| title_short |
In-hospital mortality among consecutive patients with ST-Elevation myocardial infarction in modern primary percutaneous intervention era ~ Insights from 15-year data of single-center hospital-based registry ~. |
| title_full |
In-hospital mortality among consecutive patients with ST-Elevation myocardial infarction in modern primary percutaneous intervention era ~ Insights from 15-year data of single-center hospital-based registry ~. |
| title_fullStr |
In-hospital mortality among consecutive patients with ST-Elevation myocardial infarction in modern primary percutaneous intervention era ~ Insights from 15-year data of single-center hospital-based registry ~. |
| title_full_unstemmed |
In-hospital mortality among consecutive patients with ST-Elevation myocardial infarction in modern primary percutaneous intervention era ~ Insights from 15-year data of single-center hospital-based registry ~. |
| title_sort |
in-hospital mortality among consecutive patients with st-elevation myocardial infarction in modern primary percutaneous intervention era ~ insights from 15-year data of single-center hospital-based registry ~. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2021 |
| url |
https://doaj.org/article/ee9bfe9f43f547c590434186927b8d6a |
| work_keys_str_mv |
AT kensuketakagi inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT akihitotanaka inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT naokiyoshioka inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT yasuhiromorita inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT rukayoshida inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT yasunorikanzaki inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT naokiwatanabe inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT ryotayamauchi inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT shotarokomeyama inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT hirokisugiyama inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT kazukishimojo inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT takuroimaoka inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT gakusakamoto inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT takumaohi inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT hirokigoto inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT hidekiishii inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT itsuromorishima inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry AT toyoakimurohara inhospitalmortalityamongconsecutivepatientswithstelevationmyocardialinfarctioninmodernprimarypercutaneousinterventionerainsightsfrom15yeardataofsinglecenterhospitalbasedregistry |
| _version_ |
1718375337728933888 |