Results of the home mechanical ventilation national program among adults in Chile between 2008 and 2017
Abstract Background Home mechanical ventilation (HMV) is a viable and effective strategy for patients with chronic respiratory failure (CRF). The Chilean Ministry of Health started a program for adults in 2008. Methods This study examined the following data from a prospective cohort of patients with...
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2021
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oai:doaj.org-article:eeab437f15c14b10bdea435ad2bebe772021-12-05T12:23:29ZResults of the home mechanical ventilation national program among adults in Chile between 2008 and 201710.1186/s12890-021-01764-41471-2466https://doaj.org/article/eeab437f15c14b10bdea435ad2bebe772021-12-01T00:00:00Zhttps://doi.org/10.1186/s12890-021-01764-4https://doaj.org/toc/1471-2466Abstract Background Home mechanical ventilation (HMV) is a viable and effective strategy for patients with chronic respiratory failure (CRF). The Chilean Ministry of Health started a program for adults in 2008. Methods This study examined the following data from a prospective cohort of patients with CRF admitted to the national HMV program: characteristics, mode of admission, quality of life, time in the program and survival. Results A total of 1105 patients were included. The median age was 59 years (44–58). Women accounted for 58.1% of the sample. The average body mass index (BMI) was 34.9 (26–46) kg/m2. A total of 76.2% of patients started HMV in the stable chronic mode, while 23.8% initiated HMV in the acute mode. A total of 99 patients were transferred from the children's program. There were 1047 patients on non-invasive ventilation and 58 patients on invasive ventilation. The median baseline PaCO2 level was 58.2 (52–65) mmHg. The device usage time was 7.3 h/d (5.8–8.8), and the time in HMV was 21.6 (12.2–49.5) months. The diagnoses were COPD (35%), obesity hypoventilation syndrome (OHS; 23.9%), neuromuscular disease (NMD; 16.3%), non-cystic fibrosis bronchiectasis or tuberculosis (non-CF BC or TBC; 8.3%), scoliosis (5.9%) and amyotrophic lateral sclerosis (ALS; 5.24%). The baseline score on the Severe Respiratory Insufficiency questionnaire (SRI) was 47 (± 17.9) points and significantly improved over time. The lowest 1- and 3-year survival rates were observed in the ALS group, and the lowest 9-year survival rate was observed in the non-CF BC or TB and COPD groups. The best survival rates at 9 years were OHS, scoliosis and NMD. In 2017, there were 701 patients in the children's program and 722 in the adult´s program, with a prevalence of 10.4 per 100,000 inhabitants. Conclusion The most common diagnoses were COPD and OHS. The best survival was observed in patients with OHS, scoliosis and NMD. The SRI score improved significantly in the follow-up of patients with HMV. The prevalence of HMV was 10.4 per 100,000 inhabitants. Trial registration This study was approved by and registered at the ethics committee of North Metropolitan Health Service of Santiago, Chile (N° 018/2021).César MaquilónMónica AntoliniNicolás ValdésMarianela AndradeKrishnna CanalesClaudio RabecCristian OlaveMiguel AguayoPatricia RivasCarmen AndradeÁngela VenegasSandra ZapataMaría Elena TorresOsvaldo CabreraJorge VillalobosBMCarticleHome mechanical ventilationObesity hypoventilation syndromeChronic respiratory failureDomiciliary ventilationLong term ventilationDiseases of the respiratory systemRC705-779ENBMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-12 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
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EN |
| topic |
Home mechanical ventilation Obesity hypoventilation syndrome Chronic respiratory failure Domiciliary ventilation Long term ventilation Diseases of the respiratory system RC705-779 |
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Home mechanical ventilation Obesity hypoventilation syndrome Chronic respiratory failure Domiciliary ventilation Long term ventilation Diseases of the respiratory system RC705-779 César Maquilón Mónica Antolini Nicolás Valdés Marianela Andrade Krishnna Canales Claudio Rabec Cristian Olave Miguel Aguayo Patricia Rivas Carmen Andrade Ángela Venegas Sandra Zapata María Elena Torres Osvaldo Cabrera Jorge Villalobos Results of the home mechanical ventilation national program among adults in Chile between 2008 and 2017 |
| description |
Abstract Background Home mechanical ventilation (HMV) is a viable and effective strategy for patients with chronic respiratory failure (CRF). The Chilean Ministry of Health started a program for adults in 2008. Methods This study examined the following data from a prospective cohort of patients with CRF admitted to the national HMV program: characteristics, mode of admission, quality of life, time in the program and survival. Results A total of 1105 patients were included. The median age was 59 years (44–58). Women accounted for 58.1% of the sample. The average body mass index (BMI) was 34.9 (26–46) kg/m2. A total of 76.2% of patients started HMV in the stable chronic mode, while 23.8% initiated HMV in the acute mode. A total of 99 patients were transferred from the children's program. There were 1047 patients on non-invasive ventilation and 58 patients on invasive ventilation. The median baseline PaCO2 level was 58.2 (52–65) mmHg. The device usage time was 7.3 h/d (5.8–8.8), and the time in HMV was 21.6 (12.2–49.5) months. The diagnoses were COPD (35%), obesity hypoventilation syndrome (OHS; 23.9%), neuromuscular disease (NMD; 16.3%), non-cystic fibrosis bronchiectasis or tuberculosis (non-CF BC or TBC; 8.3%), scoliosis (5.9%) and amyotrophic lateral sclerosis (ALS; 5.24%). The baseline score on the Severe Respiratory Insufficiency questionnaire (SRI) was 47 (± 17.9) points and significantly improved over time. The lowest 1- and 3-year survival rates were observed in the ALS group, and the lowest 9-year survival rate was observed in the non-CF BC or TB and COPD groups. The best survival rates at 9 years were OHS, scoliosis and NMD. In 2017, there were 701 patients in the children's program and 722 in the adult´s program, with a prevalence of 10.4 per 100,000 inhabitants. Conclusion The most common diagnoses were COPD and OHS. The best survival was observed in patients with OHS, scoliosis and NMD. The SRI score improved significantly in the follow-up of patients with HMV. The prevalence of HMV was 10.4 per 100,000 inhabitants. Trial registration This study was approved by and registered at the ethics committee of North Metropolitan Health Service of Santiago, Chile (N° 018/2021). |
| format |
article |
| author |
César Maquilón Mónica Antolini Nicolás Valdés Marianela Andrade Krishnna Canales Claudio Rabec Cristian Olave Miguel Aguayo Patricia Rivas Carmen Andrade Ángela Venegas Sandra Zapata María Elena Torres Osvaldo Cabrera Jorge Villalobos |
| author_facet |
César Maquilón Mónica Antolini Nicolás Valdés Marianela Andrade Krishnna Canales Claudio Rabec Cristian Olave Miguel Aguayo Patricia Rivas Carmen Andrade Ángela Venegas Sandra Zapata María Elena Torres Osvaldo Cabrera Jorge Villalobos |
| author_sort |
César Maquilón |
| title |
Results of the home mechanical ventilation national program among adults in Chile between 2008 and 2017 |
| title_short |
Results of the home mechanical ventilation national program among adults in Chile between 2008 and 2017 |
| title_full |
Results of the home mechanical ventilation national program among adults in Chile between 2008 and 2017 |
| title_fullStr |
Results of the home mechanical ventilation national program among adults in Chile between 2008 and 2017 |
| title_full_unstemmed |
Results of the home mechanical ventilation national program among adults in Chile between 2008 and 2017 |
| title_sort |
results of the home mechanical ventilation national program among adults in chile between 2008 and 2017 |
| publisher |
BMC |
| publishDate |
2021 |
| url |
https://doaj.org/article/eeab437f15c14b10bdea435ad2bebe77 |
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