Pharmacokinetic-Pharmacodynamic modelling of intracellular Mycobacterium tuberculosis growth and kill rates is predictive of clinical treatment duration

Abstract Tuberculosis (TB) treatment is long and complex, typically involving a combination of drugs taken for 6 months. Improved drug regimens to shorten and simplify treatment are urgently required, however a major challenge to TB drug development is the lack of predictive pre-clinical tools. To a...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ghaith Aljayyoussi, Victoria A. Jenkins, Raman Sharma, Alison Ardrey, Samantha Donnellan, Stephen A. Ward, Giancarlo A. Biagini
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/eeb7497b0cef443d825c81af2749fe7b
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!