Proteomic characterization of primary and metastatic prostate cancer reveals reduced proteinase activity in aggressive tumors
Abstract Prostate cancer (PCa) is a heterogeneous group of tumors with variable clinical courses. In order to improve patient outcomes, it is critical to clinically separate aggressive PCa (AG) from non-aggressive PCa (NAG). Although recent genomic studies have identified a spectrum of molecular abn...
Saved in:
Main Authors: | Qing Kay Li, Jing Chen, Yingwei Hu, Naseruddin Höti, Tung-Shing Mamie Lih, Stefani N. Thomas, Li Chen, Sujayita Roy, Alan Meeker, Punit Shah, Lijun Chen, G. Steven Bova, Bai Zhang, Hui Zhang |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/eec67f5b900a4b039dc046a5f2d3d03b |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The “inherent vice” in the anti-angiogenic theory may cause the highly metastatic cancer to spread more aggressively
by: Denian Wang, et al.
Published: (2017) -
Metastatic and locally aggressive BCC: Current treatment options
by: Máire‐Caitlín Casey, et al.
Published: (2021) -
Digestive duet: midgut digestive proteinases of Manduca sexta ingesting Nicotiana attenuata with manipulated trypsin proteinase inhibitor expression.
by: Jorge A Zavala, et al.
Published: (2008) -
Antiviral proteinase inhibitors of plant and animal origin
by: Valentina Divocha, et al.
Published: (2020) -
An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer
by: Rajdeep Das, et al.
Published: (2021)