Vaginal Microbiota, Genital Inflammation and Extracellular Matrix Remodelling Collagenase: MMP-9 in Pregnant Women With HIV, a Potential Preterm Birth Mechanism Warranting Further Exploration

Vaginal Microbiota, Genital Inflammation and Extracellular Matrix Remodelling Collagenase: MMP-9 in Pregnant Women With HIV, a Potential Preterm Birth Mechanism Warranting Further Exploration

BackgroundPregnant women living with HIV infection (PWLWH) have elevated rates of preterm birth (PTB) in which HIV and cART are implicated. PWLWH also have a high prevalence of adverse vaginal microbiota, which associate with genital tract inflammation. The mechanism underlying PTB in PWLWH is unkno...

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Bibliographic Details
Main Authors: Charlotte-Eve S. Short, Rachael A. Quinlan, Xuan Wang, Veronica Georgiana Preda, Ann Smith, Julian R. Marchesi, Yooni S. Lee, David A. MacIntyre, Phillip R. Bennett, Graham P. Taylor
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
HIV - human immunodeficiency virus
preterm (birth)
metalloproteinase
microbiome and dysbiosis
Gardnerella species
Microbiology
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Online Access:https://doaj.org/article/eec88b2ac81143078ce53c90bba81e6d
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https://doaj.org/article/eec88b2ac81143078ce53c90bba81e6d

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