Ca2+-activated Cl− channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration

The Ca2+-activated Cl- channel TMEM16A/Anoctamin 1 (ANO1) mediates secretion and intestinal motility in gastrointestinal epithelia and smooth muscle cells. Here, the authors show a role for ANO1 in zebrafish skeletal muscle which is activated by SR Ca2+ release during excitation-contraction coupling...

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Autores principales:	Anamika Dayal, Shu Fun J. Ng, Manfred Grabner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eecf8fc155dd48389921310afcc01f44
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spelling	oai:doaj.org-article:eecf8fc155dd48389921310afcc01f442021-12-02T16:58:15ZCa2+-activated Cl− channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration10.1038/s41467-018-07918-z2041-1723https://doaj.org/article/eecf8fc155dd48389921310afcc01f442019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07918-zhttps://doaj.org/toc/2041-1723The Ca2+-activated Cl- channel TMEM16A/Anoctamin 1 (ANO1) mediates secretion and intestinal motility in gastrointestinal epithelia and smooth muscle cells. Here, the authors show a role for ANO1 in zebrafish skeletal muscle which is activated by SR Ca2+ release during excitation-contraction coupling.Anamika DayalShu Fun J. NgManfred GrabnerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anamika Dayal Shu Fun J. Ng Manfred Grabner Ca2+-activated Cl− channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration
description	The Ca2+-activated Cl- channel TMEM16A/Anoctamin 1 (ANO1) mediates secretion and intestinal motility in gastrointestinal epithelia and smooth muscle cells. Here, the authors show a role for ANO1 in zebrafish skeletal muscle which is activated by SR Ca2+ release during excitation-contraction coupling.
format	article
author	Anamika Dayal Shu Fun J. Ng Manfred Grabner
author_facet	Anamika Dayal Shu Fun J. Ng Manfred Grabner
author_sort	Anamika Dayal
title	Ca2+-activated Cl− channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration
title_short	Ca2+-activated Cl− channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration
title_full	Ca2+-activated Cl− channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration
title_fullStr	Ca2+-activated Cl− channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration
title_full_unstemmed	Ca2+-activated Cl− channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration
title_sort	ca2+-activated cl− channel tmem16a/ano1 identified in zebrafish skeletal muscle is crucial for action potential acceleration
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/eecf8fc155dd48389921310afcc01f44
work_keys_str_mv	AT anamikadayal ca2activatedclchanneltmem16aano1identifiedinzebrafishskeletalmuscleiscrucialforactionpotentialacceleration AT shufunjng ca2activatedclchanneltmem16aano1identifiedinzebrafishskeletalmuscleiscrucialforactionpotentialacceleration AT manfredgrabner ca2activatedclchanneltmem16aano1identifiedinzebrafishskeletalmuscleiscrucialforactionpotentialacceleration
_version_	1718382363850833920

Ca2+-activated Cl− channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration

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