Physical principles of retroviral integration in the human genome

Some retroviruses, including HIV, insert their DNA in a non-random manner in the host genome through a poorly understood selection mechanism. Here the authors develop a biophysical model of retroviral integration, identifying previously unnoticed universal principles that regulate this phenomenon.

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Detalles Bibliográficos
Autores principales: D. Michieletto, M. Lusic, D. Marenduzzo, E. Orlandini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/eee16ed719ac44e5aff0f7d03eec50d5
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