Physical principles of retroviral integration in the human genome
Some retroviruses, including HIV, insert their DNA in a non-random manner in the host genome through a poorly understood selection mechanism. Here the authors develop a biophysical model of retroviral integration, identifying previously unnoticed universal principles that regulate this phenomenon.
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Autores principales: | D. Michieletto, M. Lusic, D. Marenduzzo, E. Orlandini |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/eee16ed719ac44e5aff0f7d03eec50d5 |
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