Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity

Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity

Professional antigen presenting cells (APCs) are deterred from phagocytosing cancer cells that express CD47. Here, the authors show that in glioblastoma mouse models, temozolomide improves the phagocytosis effect of CD47 blockade in APCs and results in the activation of adaptive anti-tumour response...

Full description

Saved in:
Bibliographic Details
Main Authors: Christina A. von Roemeling, Yifan Wang, Yaqing Qie, Hengfeng Yuan, Hai Zhao, Xiujie Liu, Zhaogang Yang, Mingming Yang, Weiye Deng, Katelyn A. Bruno, Charles K. Chan, Andrew S. Lee, Stephen S. Rosenfeld, Kyuson Yun, Aaron J. Johnson, Duane A. Mitchell, Wen Jiang, Betty Y. S. Kim
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
Q
Online Access:https://doaj.org/article/eee195d796b64fada2ef877b68da61fb
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/eee195d796b64fada2ef877b68da61fb

Similar Items