Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis
The structure of human tumor suppressor p53 in complex with the antiapoptotic protein BCL-xL reveals the basis of the p53–BCL-xL interaction and provides insight into the mechanisms of p53-mediated mitochondrial apoptosis.
Enregistré dans:
Auteurs principaux: | Hudie Wei, Lingzhi Qu, Shuyan Dai, Yun Li, Haolan Wang, Yilu Feng, Xiaojuan Chen, Longying Jiang, Ming Guo, Jun Li, Zhuchu Chen, Lin Chen, Ye Zhang, Yongheng Chen |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/eee86fb8caf449e7a93cc5a90e776ac6 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
RIPK1 Coordinates Bone Marrow Mesenchymal Stem Cell Survival by Maintaining Mitochondrial Homeostasis via p53
par: Qing Tian, et autres
Publié: (2021) -
The chemopreventive effects of Protandim: modulation of p53 mitochondrial translocation and apoptosis during skin carcinogenesis.
par: Delira Robbins, et autres
Publié: (2010) -
Bcl-xL Reduces Chinese Giant Salamander Iridovirus-Induced Mitochondrial Apoptosis by Interacting with Bak and Inhibiting the p53 Pathway
par: Yiqun Li, et autres
Publié: (2021) -
Pterostilbene promotes mitochondrial apoptosis and inhibits proliferation in glioma cells
par: Haijun Gao, et autres
Publié: (2021) -
Palmitic acid increases apoptosis by mitochondrial pathway in hepatocytes with growth hormone deficiency
par: WANG Yunting, et autres
Publié: (2021)