Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis

Moderate consumption of alcohol is associated with protection from some autoimmune diseases. Here the authors show that ethanol and its metabolite acetate can protect mice from collagen-induced arthritis and provide evidence that the mechanism of this effect might be via inhibition of the effector f...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Vugar Azizov, Katharina Dietel, Franziska Steffen, Kerstin Dürholz, Julia Meidenbauer, Sébastien Lucas, Michael Frech, Yasunori Omata, Narges Tajik, Lisa Knipfer, Anne Kolenbrander, Silvia Seubert, Dennis Lapuente, Maria V. Sokolova, Jörg Hofmann, Matthias Tenbusch, Andreas Ramming, Ulrike Steffen, Falk Nimmerjahn, Ralf Linker, Stefan Wirtz, Martin Herrmann, Vladimir Temchura, Kerstin Sarter, Georg Schett, Mario M. Zaiss
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eeef82bd54c54d9ebcc3a76561c3042f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:eeef82bd54c54d9ebcc3a76561c3042f
record_format	dspace
spelling	oai:doaj.org-article:eeef82bd54c54d9ebcc3a76561c3042f2021-12-02T16:50:00ZEthanol consumption inhibits TFH cell responses and the development of autoimmune arthritis10.1038/s41467-020-15855-z2041-1723https://doaj.org/article/eeef82bd54c54d9ebcc3a76561c3042f2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15855-zhttps://doaj.org/toc/2041-1723Moderate consumption of alcohol is associated with protection from some autoimmune diseases. Here the authors show that ethanol and its metabolite acetate can protect mice from collagen-induced arthritis and provide evidence that the mechanism of this effect might be via inhibition of the effector function of T follicular helper cells.Vugar AzizovKatharina DietelFranziska SteffenKerstin DürholzJulia MeidenbauerSébastien LucasMichael FrechYasunori OmataNarges TajikLisa KnipferAnne KolenbranderSilvia SeubertDennis LapuenteMaria V. SokolovaJörg HofmannMatthias TenbuschAndreas RammingUlrike SteffenFalk NimmerjahnRalf LinkerStefan WirtzMartin HerrmannVladimir TemchuraKerstin SarterGeorg SchettMario M. ZaissNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Vugar Azizov Katharina Dietel Franziska Steffen Kerstin Dürholz Julia Meidenbauer Sébastien Lucas Michael Frech Yasunori Omata Narges Tajik Lisa Knipfer Anne Kolenbrander Silvia Seubert Dennis Lapuente Maria V. Sokolova Jörg Hofmann Matthias Tenbusch Andreas Ramming Ulrike Steffen Falk Nimmerjahn Ralf Linker Stefan Wirtz Martin Herrmann Vladimir Temchura Kerstin Sarter Georg Schett Mario M. Zaiss Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis
description	Moderate consumption of alcohol is associated with protection from some autoimmune diseases. Here the authors show that ethanol and its metabolite acetate can protect mice from collagen-induced arthritis and provide evidence that the mechanism of this effect might be via inhibition of the effector function of T follicular helper cells.
format	article
author	Vugar Azizov Katharina Dietel Franziska Steffen Kerstin Dürholz Julia Meidenbauer Sébastien Lucas Michael Frech Yasunori Omata Narges Tajik Lisa Knipfer Anne Kolenbrander Silvia Seubert Dennis Lapuente Maria V. Sokolova Jörg Hofmann Matthias Tenbusch Andreas Ramming Ulrike Steffen Falk Nimmerjahn Ralf Linker Stefan Wirtz Martin Herrmann Vladimir Temchura Kerstin Sarter Georg Schett Mario M. Zaiss
author_facet	Vugar Azizov Katharina Dietel Franziska Steffen Kerstin Dürholz Julia Meidenbauer Sébastien Lucas Michael Frech Yasunori Omata Narges Tajik Lisa Knipfer Anne Kolenbrander Silvia Seubert Dennis Lapuente Maria V. Sokolova Jörg Hofmann Matthias Tenbusch Andreas Ramming Ulrike Steffen Falk Nimmerjahn Ralf Linker Stefan Wirtz Martin Herrmann Vladimir Temchura Kerstin Sarter Georg Schett Mario M. Zaiss
author_sort	Vugar Azizov
title	Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis
title_short	Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis
title_full	Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis
title_fullStr	Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis
title_full_unstemmed	Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis
title_sort	ethanol consumption inhibits tfh cell responses and the development of autoimmune arthritis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/eeef82bd54c54d9ebcc3a76561c3042f
work_keys_str_mv	AT vugarazizov ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT katharinadietel ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT franziskasteffen ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT kerstindurholz ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT juliameidenbauer ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT sebastienlucas ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT michaelfrech ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT yasunoriomata ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT nargestajik ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT lisaknipfer ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT annekolenbrander ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT silviaseubert ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT dennislapuente ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT mariavsokolova ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT jorghofmann ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT matthiastenbusch ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT andreasramming ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT ulrikesteffen ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT falknimmerjahn ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT ralflinker ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT stefanwirtz ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT martinherrmann ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT vladimirtemchura ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT kerstinsarter ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT georgschett ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis AT mariomzaiss ethanolconsumptioninhibitstfhcellresponsesandthedevelopmentofautoimmunearthritis
_version_	1718383192423006208

Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis

Ejemplares similares