Single-cell transcriptomic analysis of mouse neocortical development

The authors perform single-cell RNA-seq of the mouse neocortex at an embryonic time point and at birth, and identify new and known cell types, and cell relatedness within and across age. These data serve as a resource to understand brain development and the cellular origins of brain diseases.

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Autores principales: Lipin Loo, Jeremy M. Simon, Lei Xing, Eric S. McCoy, Jesse K. Niehaus, Jiami Guo, E. S. Anton, Mark J. Zylka
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/eef916514df749ae928a6eaa25a3d703
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spelling oai:doaj.org-article:eef916514df749ae928a6eaa25a3d7032021-12-02T17:02:02ZSingle-cell transcriptomic analysis of mouse neocortical development10.1038/s41467-018-08079-92041-1723https://doaj.org/article/eef916514df749ae928a6eaa25a3d7032019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08079-9https://doaj.org/toc/2041-1723The authors perform single-cell RNA-seq of the mouse neocortex at an embryonic time point and at birth, and identify new and known cell types, and cell relatedness within and across age. These data serve as a resource to understand brain development and the cellular origins of brain diseases.Lipin LooJeremy M. SimonLei XingEric S. McCoyJesse K. NiehausJiami GuoE. S. AntonMark J. ZylkaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lipin Loo
Jeremy M. Simon
Lei Xing
Eric S. McCoy
Jesse K. Niehaus
Jiami Guo
E. S. Anton
Mark J. Zylka
Single-cell transcriptomic analysis of mouse neocortical development
description The authors perform single-cell RNA-seq of the mouse neocortex at an embryonic time point and at birth, and identify new and known cell types, and cell relatedness within and across age. These data serve as a resource to understand brain development and the cellular origins of brain diseases.
format article
author Lipin Loo
Jeremy M. Simon
Lei Xing
Eric S. McCoy
Jesse K. Niehaus
Jiami Guo
E. S. Anton
Mark J. Zylka
author_facet Lipin Loo
Jeremy M. Simon
Lei Xing
Eric S. McCoy
Jesse K. Niehaus
Jiami Guo
E. S. Anton
Mark J. Zylka
author_sort Lipin Loo
title Single-cell transcriptomic analysis of mouse neocortical development
title_short Single-cell transcriptomic analysis of mouse neocortical development
title_full Single-cell transcriptomic analysis of mouse neocortical development
title_fullStr Single-cell transcriptomic analysis of mouse neocortical development
title_full_unstemmed Single-cell transcriptomic analysis of mouse neocortical development
title_sort single-cell transcriptomic analysis of mouse neocortical development
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/eef916514df749ae928a6eaa25a3d703
work_keys_str_mv AT lipinloo singlecelltranscriptomicanalysisofmouseneocorticaldevelopment
AT jeremymsimon singlecelltranscriptomicanalysisofmouseneocorticaldevelopment
AT leixing singlecelltranscriptomicanalysisofmouseneocorticaldevelopment
AT ericsmccoy singlecelltranscriptomicanalysisofmouseneocorticaldevelopment
AT jessekniehaus singlecelltranscriptomicanalysisofmouseneocorticaldevelopment
AT jiamiguo singlecelltranscriptomicanalysisofmouseneocorticaldevelopment
AT esanton singlecelltranscriptomicanalysisofmouseneocorticaldevelopment
AT markjzylka singlecelltranscriptomicanalysisofmouseneocorticaldevelopment
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