Roflumilast inhibits respiratory syncytial virus infection in human differentiated bronchial epithelial cells.

Roflumilast inhibits respiratory syncytial virus infection in human differentiated bronchial epithelial cells.

Respiratory syncytial virus (RSV) causes acute exacerbations in COPD and asthma. RSV infects bronchial epithelial cells (HBE) that trigger RSV associated lung pathology. This study explores whether the phosphodiesterase 4 (PDE4) inhibitor Roflumilast N-oxide (RNO), alters RSV infection of well-diffe...

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Autores principales: Manuel Mata, Isidoro Martinez, Jose A Melero, Herman Tenor, Julio Cortijo
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/eeffae9a83494ce4973afe8664160734
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