Entropy of a bacterial stress response is a generalizable predictor for fitness and antibiotic sensitivity
Bacterial transcriptomic data have been used to predict antibiotic susceptibility in a species- or antibiotic-specific manner. Here, the authors show that global transcriptional disorder is a common stress response in bacteria with low fitness, and present a general approach that can predict bacteri...
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Autores principales: | Zeyu Zhu, Defne Surujon, Juan C. Ortiz-Marquez, Wenwen Huo, Ralph R. Isberg, José Bento, Tim van Opijnen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/ef0fe239e15245d990fc0ccfb009ce26 |
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