Complement Component 3C3 and C3a Receptor Are Required in Chitin-Dependent Allergic Sensitization to <named-content content-type="genus-species">Aspergillus fumigatus</named-content> but Dispensable in Chitin-Induced Innate Allergic Inflammation

Complement Component 3C3 and C3a Receptor Are Required in Chitin-Dependent Allergic Sensitization to <named-content content-type="genus-species">Aspergillus fumigatus</named-content> but Dispensable in Chitin-Induced Innate Allergic Inflammation

ABSTRACT Levels of the anaphylatoxin C3a are increased in patients with asthma compared with those in nonasthmatics and increase further still during asthma exacerbations. However, the role of C3a during sensitization to allergen is poorly understood. Sensitization to fungal allergens, such as Asper...

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Autores principales: René M. Roy, Hugo C. Paes, Som G. Nanjappa, Ron Sorkness, David Gasper, Alana Sterkel, Marcel Wüthrich, Bruce S. Klein
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2013
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/ef1080b5d70d4432b8f6ec4bc618dd2c
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