Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data

Intra-tumour heterogeneity provides important information about subclonal tumour evolution. Here, the authors develop B-SCITE, a computational method for inferring tumour phylogenies from combined single-cell and bulk sequencing data.

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Autores principales:	Salem Malikic, Katharina Jahn, Jack Kuipers, S. Cenk Sahinalp, Niko Beerenwinkel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ef258a1885df4088abb09ed93505c2e3
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spelling	oai:doaj.org-article:ef258a1885df4088abb09ed93505c2e32021-12-02T14:35:44ZIntegrative inference of subclonal tumour evolution from single-cell and bulk sequencing data10.1038/s41467-019-10737-52041-1723https://doaj.org/article/ef258a1885df4088abb09ed93505c2e32019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10737-5https://doaj.org/toc/2041-1723Intra-tumour heterogeneity provides important information about subclonal tumour evolution. Here, the authors develop B-SCITE, a computational method for inferring tumour phylogenies from combined single-cell and bulk sequencing data.Salem MalikicKatharina JahnJack KuipersS. Cenk SahinalpNiko BeerenwinkelNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Salem Malikic Katharina Jahn Jack Kuipers S. Cenk Sahinalp Niko Beerenwinkel Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data
description	Intra-tumour heterogeneity provides important information about subclonal tumour evolution. Here, the authors develop B-SCITE, a computational method for inferring tumour phylogenies from combined single-cell and bulk sequencing data.
format	article
author	Salem Malikic Katharina Jahn Jack Kuipers S. Cenk Sahinalp Niko Beerenwinkel
author_facet	Salem Malikic Katharina Jahn Jack Kuipers S. Cenk Sahinalp Niko Beerenwinkel
author_sort	Salem Malikic
title	Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data
title_short	Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data
title_full	Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data
title_fullStr	Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data
title_full_unstemmed	Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data
title_sort	integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ef258a1885df4088abb09ed93505c2e3
work_keys_str_mv	AT salemmalikic integrativeinferenceofsubclonaltumourevolutionfromsinglecellandbulksequencingdata AT katharinajahn integrativeinferenceofsubclonaltumourevolutionfromsinglecellandbulksequencingdata AT jackkuipers integrativeinferenceofsubclonaltumourevolutionfromsinglecellandbulksequencingdata AT scenksahinalp integrativeinferenceofsubclonaltumourevolutionfromsinglecellandbulksequencingdata AT nikobeerenwinkel integrativeinferenceofsubclonaltumourevolutionfromsinglecellandbulksequencingdata
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Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data

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