Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data

Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data

Intra-tumour heterogeneity provides important information about subclonal tumour evolution. Here, the authors develop B-SCITE, a computational method for inferring tumour phylogenies from combined single-cell and bulk sequencing data.

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Detalles Bibliográficos
Autores principales: Salem Malikic, Katharina Jahn, Jack Kuipers, S. Cenk Sahinalp, Niko Beerenwinkel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
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Acceso en línea:https://doaj.org/article/ef258a1885df4088abb09ed93505c2e3
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