Initiation of cytosolic plant purine nucleotide catabolism involves a monospecific xanthosine monophosphate phosphatase

Dephosphorylation of xanthosine monophosphate (XMP) initiates purine nucleotide catabolism in plant cells. Here the authors identify an XMP phosphatase from Arabidopsis that channels XMP towards catabolism in vivo and demonstrate the structural basis for its XMP specificity.

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Autores principales: Katharina J. Heinemann, Sun-Young Yang, Henryk Straube, Nieves Medina-Escobar, Marina Varbanova-Herde, Marco Herde, Sangkee Rhee, Claus-Peter Witte
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ef27b21a618645b88b66288c1dce66e9
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spelling oai:doaj.org-article:ef27b21a618645b88b66288c1dce66e92021-11-28T12:33:11ZInitiation of cytosolic plant purine nucleotide catabolism involves a monospecific xanthosine monophosphate phosphatase10.1038/s41467-021-27152-42041-1723https://doaj.org/article/ef27b21a618645b88b66288c1dce66e92021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27152-4https://doaj.org/toc/2041-1723Dephosphorylation of xanthosine monophosphate (XMP) initiates purine nucleotide catabolism in plant cells. Here the authors identify an XMP phosphatase from Arabidopsis that channels XMP towards catabolism in vivo and demonstrate the structural basis for its XMP specificity.Katharina J. HeinemannSun-Young YangHenryk StraubeNieves Medina-EscobarMarina Varbanova-HerdeMarco HerdeSangkee RheeClaus-Peter WitteNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Katharina J. Heinemann
Sun-Young Yang
Henryk Straube
Nieves Medina-Escobar
Marina Varbanova-Herde
Marco Herde
Sangkee Rhee
Claus-Peter Witte
Initiation of cytosolic plant purine nucleotide catabolism involves a monospecific xanthosine monophosphate phosphatase
description Dephosphorylation of xanthosine monophosphate (XMP) initiates purine nucleotide catabolism in plant cells. Here the authors identify an XMP phosphatase from Arabidopsis that channels XMP towards catabolism in vivo and demonstrate the structural basis for its XMP specificity.
format article
author Katharina J. Heinemann
Sun-Young Yang
Henryk Straube
Nieves Medina-Escobar
Marina Varbanova-Herde
Marco Herde
Sangkee Rhee
Claus-Peter Witte
author_facet Katharina J. Heinemann
Sun-Young Yang
Henryk Straube
Nieves Medina-Escobar
Marina Varbanova-Herde
Marco Herde
Sangkee Rhee
Claus-Peter Witte
author_sort Katharina J. Heinemann
title Initiation of cytosolic plant purine nucleotide catabolism involves a monospecific xanthosine monophosphate phosphatase
title_short Initiation of cytosolic plant purine nucleotide catabolism involves a monospecific xanthosine monophosphate phosphatase
title_full Initiation of cytosolic plant purine nucleotide catabolism involves a monospecific xanthosine monophosphate phosphatase
title_fullStr Initiation of cytosolic plant purine nucleotide catabolism involves a monospecific xanthosine monophosphate phosphatase
title_full_unstemmed Initiation of cytosolic plant purine nucleotide catabolism involves a monospecific xanthosine monophosphate phosphatase
title_sort initiation of cytosolic plant purine nucleotide catabolism involves a monospecific xanthosine monophosphate phosphatase
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/ef27b21a618645b88b66288c1dce66e9
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AT henrykstraube initiationofcytosolicplantpurinenucleotidecatabolisminvolvesamonospecificxanthosinemonophosphatephosphatase
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