Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex

The pyruvate dehydrogenase complex (PDC) is a multienzyme complex connecting glycolysis to mitochondrial oxidation of pyruvate. Cryo-EM analysis of PDC from Neurospora crassa reveals localization of fungi-specific protein X (PX) and confirms that it functions like the mammalian E3BP, recruiting the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: B. O. Forsberg, S. Aibara, R. J. Howard, N. Mortezaei, E. Lindahl
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/ef295762d5314830a67e8da8137ed4f0
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:ef295762d5314830a67e8da8137ed4f0
record_format dspace
spelling oai:doaj.org-article:ef295762d5314830a67e8da8137ed4f02021-12-02T18:02:16ZArrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex10.1038/s41467-020-18401-z2041-1723https://doaj.org/article/ef295762d5314830a67e8da8137ed4f02020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18401-zhttps://doaj.org/toc/2041-1723The pyruvate dehydrogenase complex (PDC) is a multienzyme complex connecting glycolysis to mitochondrial oxidation of pyruvate. Cryo-EM analysis of PDC from Neurospora crassa reveals localization of fungi-specific protein X (PX) and confirms that it functions like the mammalian E3BP, recruiting the E3 component of PDC.B. O. ForsbergS. AibaraR. J. HowardN. MortezaeiE. LindahlNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
B. O. Forsberg
S. Aibara
R. J. Howard
N. Mortezaei
E. Lindahl
Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex
description The pyruvate dehydrogenase complex (PDC) is a multienzyme complex connecting glycolysis to mitochondrial oxidation of pyruvate. Cryo-EM analysis of PDC from Neurospora crassa reveals localization of fungi-specific protein X (PX) and confirms that it functions like the mammalian E3BP, recruiting the E3 component of PDC.
format article
author B. O. Forsberg
S. Aibara
R. J. Howard
N. Mortezaei
E. Lindahl
author_facet B. O. Forsberg
S. Aibara
R. J. Howard
N. Mortezaei
E. Lindahl
author_sort B. O. Forsberg
title Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex
title_short Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex
title_full Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex
title_fullStr Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex
title_full_unstemmed Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex
title_sort arrangement and symmetry of the fungal e3bp-containing core of the pyruvate dehydrogenase complex
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/ef295762d5314830a67e8da8137ed4f0
work_keys_str_mv AT boforsberg arrangementandsymmetryofthefungale3bpcontainingcoreofthepyruvatedehydrogenasecomplex
AT saibara arrangementandsymmetryofthefungale3bpcontainingcoreofthepyruvatedehydrogenasecomplex
AT rjhoward arrangementandsymmetryofthefungale3bpcontainingcoreofthepyruvatedehydrogenasecomplex
AT nmortezaei arrangementandsymmetryofthefungale3bpcontainingcoreofthepyruvatedehydrogenasecomplex
AT elindahl arrangementandsymmetryofthefungale3bpcontainingcoreofthepyruvatedehydrogenasecomplex
_version_ 1718378962849103872