Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex
The pyruvate dehydrogenase complex (PDC) is a multienzyme complex connecting glycolysis to mitochondrial oxidation of pyruvate. Cryo-EM analysis of PDC from Neurospora crassa reveals localization of fungi-specific protein X (PX) and confirms that it functions like the mammalian E3BP, recruiting the...
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2020
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oai:doaj.org-article:ef295762d5314830a67e8da8137ed4f02021-12-02T18:02:16ZArrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex10.1038/s41467-020-18401-z2041-1723https://doaj.org/article/ef295762d5314830a67e8da8137ed4f02020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18401-zhttps://doaj.org/toc/2041-1723The pyruvate dehydrogenase complex (PDC) is a multienzyme complex connecting glycolysis to mitochondrial oxidation of pyruvate. Cryo-EM analysis of PDC from Neurospora crassa reveals localization of fungi-specific protein X (PX) and confirms that it functions like the mammalian E3BP, recruiting the E3 component of PDC.B. O. ForsbergS. AibaraR. J. HowardN. MortezaeiE. LindahlNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
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Science Q B. O. Forsberg S. Aibara R. J. Howard N. Mortezaei E. Lindahl Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex |
description |
The pyruvate dehydrogenase complex (PDC) is a multienzyme complex connecting glycolysis to mitochondrial oxidation of pyruvate. Cryo-EM analysis of PDC from Neurospora crassa reveals localization of fungi-specific protein X (PX) and confirms that it functions like the mammalian E3BP, recruiting the E3 component of PDC. |
format |
article |
author |
B. O. Forsberg S. Aibara R. J. Howard N. Mortezaei E. Lindahl |
author_facet |
B. O. Forsberg S. Aibara R. J. Howard N. Mortezaei E. Lindahl |
author_sort |
B. O. Forsberg |
title |
Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex |
title_short |
Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex |
title_full |
Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex |
title_fullStr |
Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex |
title_full_unstemmed |
Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex |
title_sort |
arrangement and symmetry of the fungal e3bp-containing core of the pyruvate dehydrogenase complex |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/ef295762d5314830a67e8da8137ed4f0 |
work_keys_str_mv |
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_version_ |
1718378962849103872 |