The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA

Termination of RNA polymerase II is a critical step in transcription. Here, the authors provide evidence that the fission yeast CID-RRM protein Seb1 is required for termination of coding and non-coding genes through interaction with both the polymerase and the nascent RNA.

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Autores principales: Sina Wittmann, Max Renner, Beth R. Watts, Oliver Adams, Miles Huseyin, Carlo Baejen, Kamel El Omari, Cornelia Kilchert, Dong-Hyuk Heo, Tea Kecman, Patrick Cramer, Jonathan M. Grimes, Lidia Vasiljeva
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Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/ef394db5756b48a9bb4c2015dc21a112
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spelling oai:doaj.org-article:ef394db5756b48a9bb4c2015dc21a1122021-12-02T15:37:01ZThe conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA10.1038/ncomms148612041-1723https://doaj.org/article/ef394db5756b48a9bb4c2015dc21a1122017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14861https://doaj.org/toc/2041-1723Termination of RNA polymerase II is a critical step in transcription. Here, the authors provide evidence that the fission yeast CID-RRM protein Seb1 is required for termination of coding and non-coding genes through interaction with both the polymerase and the nascent RNA.Sina WittmannMax RennerBeth R. WattsOliver AdamsMiles HuseyinCarlo BaejenKamel El OmariCornelia KilchertDong-Hyuk HeoTea KecmanPatrick CramerJonathan M. GrimesLidia VasiljevaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sina Wittmann
Max Renner
Beth R. Watts
Oliver Adams
Miles Huseyin
Carlo Baejen
Kamel El Omari
Cornelia Kilchert
Dong-Hyuk Heo
Tea Kecman
Patrick Cramer
Jonathan M. Grimes
Lidia Vasiljeva
The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA
description Termination of RNA polymerase II is a critical step in transcription. Here, the authors provide evidence that the fission yeast CID-RRM protein Seb1 is required for termination of coding and non-coding genes through interaction with both the polymerase and the nascent RNA.
format article
author Sina Wittmann
Max Renner
Beth R. Watts
Oliver Adams
Miles Huseyin
Carlo Baejen
Kamel El Omari
Cornelia Kilchert
Dong-Hyuk Heo
Tea Kecman
Patrick Cramer
Jonathan M. Grimes
Lidia Vasiljeva
author_facet Sina Wittmann
Max Renner
Beth R. Watts
Oliver Adams
Miles Huseyin
Carlo Baejen
Kamel El Omari
Cornelia Kilchert
Dong-Hyuk Heo
Tea Kecman
Patrick Cramer
Jonathan M. Grimes
Lidia Vasiljeva
author_sort Sina Wittmann
title The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA
title_short The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA
title_full The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA
title_fullStr The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA
title_full_unstemmed The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA
title_sort conserved protein seb1 drives transcription termination by binding rna polymerase ii and nascent rna
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/ef394db5756b48a9bb4c2015dc21a112
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