Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state

CD4+ T cells contain a T-bethigh memory-phenotype (MP) population with innate-like functions. Here the authors characterize the requirements for their differentiation at homeostasis and identify a function for IL-12 that is tonically produced by type 1 dendritic cells in an MyD88- and CD40-dependent...

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Bibliographic Details
Main Authors: Takeshi Kawabe, Jaeu Yi, Akihisa Kawajiri, Kerry Hilligan, Difeng Fang, Naoto Ishii, Hidehiro Yamane, Jinfang Zhu, Dragana Jankovic, Kwang Soon Kim, Giorgio Trinchieri, Alan Sher
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/ef3cb49a011444f1ac9d73d4ce336452
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