Convergent evolution of a genomic rearrangement may explain cancer resistance in hystrico- and sciuromorpha rodents

Convergent evolution of a genomic rearrangement may explain cancer resistance in hystrico- and sciuromorpha rodents

Abstract The rodents of hystricomorpha and sciuromorpha suborders exhibit remarkably lower incidence of cancer. The underlying genetic basis remains obscure. We report a convergent evolutionary split of human 3p21.31, a locus hosting a large number of tumour-suppressor genes (TSGs) and frequently de...

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Autores principales: Yachna Jain, Keerthivasan Raanin Chandradoss, Anjoom A. V., Jui Bhattacharya, Mohan Lal, Meenakshi Bagadia, Harpreet Singh, Kuljeet Singh Sandhu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Geriatrics
RC952-954.6
Acceso en línea:https://doaj.org/article/ef48398f433c4d418e7292a983c20452
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