Transcriptome-wide association study uncovers the role of essential genes in anthracycline-induced cardiotoxicity

Transcriptome-wide association study uncovers the role of essential genes in anthracycline-induced cardiotoxicity

Abstract Anthracyclines are highly effective chemotherapeutic agents; however, their clinical utility is limited by severe anthracycline-induced cardiotoxicity (ACT). Genome-wide association studies (GWAS) have uncovered several genetic variants associated with ACT, but the impact of these findings...

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Autores principales: Erika N. Scott, Galen E. B. Wright, Britt I. Drögemöller, Jafar S. Hasbullah, Erandika P. Gunaretnam, Fudan Miao, Amit P. Bhavsar, Fei Shen, Bryan P. Schneider, Bruce C. Carleton, Colin J. D. Ross
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/ef67d46dd6034a2687778555b536d940
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https://doaj.org/article/ef67d46dd6034a2687778555b536d940

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