Extramammary Paget’s Disease in the Genital Area of a Male: A Case Report and Review of the Literature

Extramammary Paget’s disease (EMPD) is an uncommon intraepithelial malignancy that is rarely found in the male. Currently, there is very little knowledge pertaining to EMPD imaging, particularly in cases that involve the scrotum. Here, a 67-year-old man with lichenification on his left scrotum confi...

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Autores principales:	Dan Zhao, Bo-ping Wen, Sen-yin Xu
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	extramammary Paget disease (EMPD) conventional ultrasonography (US) contrast-enhanced ultrasound (CEUS) scrotum imaging findings Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/ef6b9159801945aca243664371173219
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id	oai:doaj.org-article:ef6b9159801945aca243664371173219
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spelling	oai:doaj.org-article:ef6b9159801945aca2436643711732192021-11-04T05:49:18ZExtramammary Paget’s Disease in the Genital Area of a Male: A Case Report and Review of the Literature2234-943X10.3389/fonc.2021.713786https://doaj.org/article/ef6b9159801945aca2436643711732192021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.713786/fullhttps://doaj.org/toc/2234-943XExtramammary Paget’s disease (EMPD) is an uncommon intraepithelial malignancy that is rarely found in the male. Currently, there is very little knowledge pertaining to EMPD imaging, particularly in cases that involve the scrotum. Here, a 67-year-old man with lichenification on his left scrotum confirmed to be EMPD was reviewed. Bloodwork did not return a positive result, but syphilis-specific antibodies were found. Conventional high-frequency ultrasound (US) and contrast-enhanced ultrasound (CEUS) imaging were utilized to determine the lesion size and blood perfusion. In the present case, the lesion’s size and involvement were vividly depicted by CEUS, while results obtained by conventional US were grossly underestimated. Consequently, multimodal imaging assessment is likely to provide more accurate diagnoses for uncommon diseases, such as EMPD, and to aid in clinical decision-making.Dan ZhaoBo-ping WenSen-yin XuFrontiers Media S.A.articleextramammary Paget disease (EMPD)conventional ultrasonography (US)contrast-enhanced ultrasound (CEUS)scrotumimaging findingsNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	extramammary Paget disease (EMPD) conventional ultrasonography (US) contrast-enhanced ultrasound (CEUS) scrotum imaging findings Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	extramammary Paget disease (EMPD) conventional ultrasonography (US) contrast-enhanced ultrasound (CEUS) scrotum imaging findings Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Dan Zhao Bo-ping Wen Sen-yin Xu Extramammary Paget’s Disease in the Genital Area of a Male: A Case Report and Review of the Literature
description	Extramammary Paget’s disease (EMPD) is an uncommon intraepithelial malignancy that is rarely found in the male. Currently, there is very little knowledge pertaining to EMPD imaging, particularly in cases that involve the scrotum. Here, a 67-year-old man with lichenification on his left scrotum confirmed to be EMPD was reviewed. Bloodwork did not return a positive result, but syphilis-specific antibodies were found. Conventional high-frequency ultrasound (US) and contrast-enhanced ultrasound (CEUS) imaging were utilized to determine the lesion size and blood perfusion. In the present case, the lesion’s size and involvement were vividly depicted by CEUS, while results obtained by conventional US were grossly underestimated. Consequently, multimodal imaging assessment is likely to provide more accurate diagnoses for uncommon diseases, such as EMPD, and to aid in clinical decision-making.
format	article
author	Dan Zhao Bo-ping Wen Sen-yin Xu
author_facet	Dan Zhao Bo-ping Wen Sen-yin Xu
author_sort	Dan Zhao
title	Extramammary Paget’s Disease in the Genital Area of a Male: A Case Report and Review of the Literature
title_short	Extramammary Paget’s Disease in the Genital Area of a Male: A Case Report and Review of the Literature
title_full	Extramammary Paget’s Disease in the Genital Area of a Male: A Case Report and Review of the Literature
title_fullStr	Extramammary Paget’s Disease in the Genital Area of a Male: A Case Report and Review of the Literature
title_full_unstemmed	Extramammary Paget’s Disease in the Genital Area of a Male: A Case Report and Review of the Literature
title_sort	extramammary paget’s disease in the genital area of a male: a case report and review of the literature
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/ef6b9159801945aca243664371173219
work_keys_str_mv	AT danzhao extramammarypagetsdiseaseinthegenitalareaofamaleacasereportandreviewoftheliterature AT bopingwen extramammarypagetsdiseaseinthegenitalareaofamaleacasereportandreviewoftheliterature AT senyinxu extramammarypagetsdiseaseinthegenitalareaofamaleacasereportandreviewoftheliterature
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Extramammary Paget’s Disease in the Genital Area of a Male: A Case Report and Review of the Literature

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