Quantitative tRNA-sequencing uncovers metazoan tissue-specific tRNA regulation

The relative abundance of specific tRNA can impact protein production rate, folding, and messenger RNA stability. Here the authors describe QuantM-tRNA seq — a method to monitor tRNA abundance and sequence variants — and uncover distinctions in isodecoder expression between tissues that are independ...

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Autores principales: Otis Pinkard, Sean McFarland, Thomas Sweet, Jeff Coller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ef707c41b35c4390a78986746ab795bd
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