Nanocrystal facet modulation to enhance transferrin binding and cellular delivery

Modulation of exposed crystal facets enhances transferrin binding to chalcogenide nanocrystals and their subsequent delivery into cancer cells. Facet-dependent protein binding occurs through inner-sphere thiol complexation and is affected by the structure of the first solvation shell.

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Detalles Bibliográficos
Autores principales: Yu Qi, Tong Zhang, Chuanyong Jing, Sijin Liu, Chengdong Zhang, Pedro J. J. Alvarez, Wei Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ef85a9a2b3904083a9ff5d35f3a94434
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Sumario:Modulation of exposed crystal facets enhances transferrin binding to chalcogenide nanocrystals and their subsequent delivery into cancer cells. Facet-dependent protein binding occurs through inner-sphere thiol complexation and is affected by the structure of the first solvation shell.