Nanocrystal facet modulation to enhance transferrin binding and cellular delivery
Modulation of exposed crystal facets enhances transferrin binding to chalcogenide nanocrystals and their subsequent delivery into cancer cells. Facet-dependent protein binding occurs through inner-sphere thiol complexation and is affected by the structure of the first solvation shell.
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Nature Portfolio
2020
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oai:doaj.org-article:ef85a9a2b3904083a9ff5d35f3a944342021-12-02T16:49:28ZNanocrystal facet modulation to enhance transferrin binding and cellular delivery10.1038/s41467-020-14972-z2041-1723https://doaj.org/article/ef85a9a2b3904083a9ff5d35f3a944342020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14972-zhttps://doaj.org/toc/2041-1723Modulation of exposed crystal facets enhances transferrin binding to chalcogenide nanocrystals and their subsequent delivery into cancer cells. Facet-dependent protein binding occurs through inner-sphere thiol complexation and is affected by the structure of the first solvation shell.Yu QiTong ZhangChuanyong JingSijin LiuChengdong ZhangPedro J. J. AlvarezWei ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
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Science Q |
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Science Q Yu Qi Tong Zhang Chuanyong Jing Sijin Liu Chengdong Zhang Pedro J. J. Alvarez Wei Chen Nanocrystal facet modulation to enhance transferrin binding and cellular delivery |
description |
Modulation of exposed crystal facets enhances transferrin binding to chalcogenide nanocrystals and their subsequent delivery into cancer cells. Facet-dependent protein binding occurs through inner-sphere thiol complexation and is affected by the structure of the first solvation shell. |
format |
article |
author |
Yu Qi Tong Zhang Chuanyong Jing Sijin Liu Chengdong Zhang Pedro J. J. Alvarez Wei Chen |
author_facet |
Yu Qi Tong Zhang Chuanyong Jing Sijin Liu Chengdong Zhang Pedro J. J. Alvarez Wei Chen |
author_sort |
Yu Qi |
title |
Nanocrystal facet modulation to enhance transferrin binding and cellular delivery |
title_short |
Nanocrystal facet modulation to enhance transferrin binding and cellular delivery |
title_full |
Nanocrystal facet modulation to enhance transferrin binding and cellular delivery |
title_fullStr |
Nanocrystal facet modulation to enhance transferrin binding and cellular delivery |
title_full_unstemmed |
Nanocrystal facet modulation to enhance transferrin binding and cellular delivery |
title_sort |
nanocrystal facet modulation to enhance transferrin binding and cellular delivery |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/ef85a9a2b3904083a9ff5d35f3a94434 |
work_keys_str_mv |
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1718383371357257728 |