Quantitative Proteome Analysis of <italic toggle="yes">Atg5</italic>-Deficient Mouse Embryonic Fibroblasts Reveals the Range of the Autophagy-Modulated Basal Cellular Proteome

Quantitative Proteome Analysis of <italic toggle="yes">Atg5</italic>-Deficient Mouse Embryonic Fibroblasts Reveals the Range of the Autophagy-Modulated Basal Cellular Proteome

ABSTRACT Basal autophagy is crucial for maintenance of cellular homeostasis. ATG5 is an essential protein for autophagosome formation, and its depletion has been extensively used as a tool to disrupt autophagy. Here, we characterize the impact of Atg5 deficiency on the cellular proteome of mouse emb...

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Autores principales: Kiran Bala Sharma, Manish Sharma, Suruchi Aggarwal, Amit Kumar Yadav, Shinjini Bhatnagar, Sudhanshu Vrati, Manjula Kalia
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
Atg5
IL-6
JAK-STAT
TLR2
TMT mass spectrometry
cell adhesion
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/ef8a5037fb3d49e8a375a55a264e36a4
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