Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors
Hearing requires mechanosensitive hair cells in the organ of Corti, which derive from progenitors of the cochlear duct. Here the authors examine human inner ear development by studying key developmental markers and describe organoid cultures from human cochlear duct progenitors for in vitro hair cel...
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Nature Portfolio
2018
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oai:doaj.org-article:ef8b80e88905450bad32986f1237e72b2021-12-02T16:56:59ZMolecular characterization and prospective isolation of human fetal cochlear hair cell progenitors10.1038/s41467-018-06334-72041-1723https://doaj.org/article/ef8b80e88905450bad32986f1237e72b2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06334-7https://doaj.org/toc/2041-1723Hearing requires mechanosensitive hair cells in the organ of Corti, which derive from progenitors of the cochlear duct. Here the authors examine human inner ear development by studying key developmental markers and describe organoid cultures from human cochlear duct progenitors for in vitro hair cell differentiation.Marta RoccioMichael PernyMegan EalyHans Ruedi WidmerStefan HellerPascal SennNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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Science Q Marta Roccio Michael Perny Megan Ealy Hans Ruedi Widmer Stefan Heller Pascal Senn Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors |
description |
Hearing requires mechanosensitive hair cells in the organ of Corti, which derive from progenitors of the cochlear duct. Here the authors examine human inner ear development by studying key developmental markers and describe organoid cultures from human cochlear duct progenitors for in vitro hair cell differentiation. |
format |
article |
author |
Marta Roccio Michael Perny Megan Ealy Hans Ruedi Widmer Stefan Heller Pascal Senn |
author_facet |
Marta Roccio Michael Perny Megan Ealy Hans Ruedi Widmer Stefan Heller Pascal Senn |
author_sort |
Marta Roccio |
title |
Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors |
title_short |
Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors |
title_full |
Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors |
title_fullStr |
Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors |
title_full_unstemmed |
Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors |
title_sort |
molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/ef8b80e88905450bad32986f1237e72b |
work_keys_str_mv |
AT martaroccio molecularcharacterizationandprospectiveisolationofhumanfetalcochlearhaircellprogenitors AT michaelperny molecularcharacterizationandprospectiveisolationofhumanfetalcochlearhaircellprogenitors AT meganealy molecularcharacterizationandprospectiveisolationofhumanfetalcochlearhaircellprogenitors AT hansruediwidmer molecularcharacterizationandprospectiveisolationofhumanfetalcochlearhaircellprogenitors AT stefanheller molecularcharacterizationandprospectiveisolationofhumanfetalcochlearhaircellprogenitors AT pascalsenn molecularcharacterizationandprospectiveisolationofhumanfetalcochlearhaircellprogenitors |
_version_ |
1718382715657519104 |