Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy

A balance between high stability and rapid degradation is required for effective photothermal anti-cancer agents. Here, the authors use Cu2+ to accelerate the degradation of black phosphorus nanosheets while enhancing its photothermal ability and apply this material for PET-guided, CDT-enhanced comb...

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Autores principales: Kuan Hu, Lin Xie, Yiding Zhang, Masayuki Hanyu, Zhimin Yang, Kotaro Nagatsu, Hisashi Suzuki, Jiang Ouyang, Xiaoyuan Ji, Junjie Wei, Hao Xu, Omid C. Farokhzad, Steven H. Liang, Lu Wang, Wei Tao, Ming-Rong Zhang
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ef8f904249e64bcdb1e38f5a9602df07
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spelling oai:doaj.org-article:ef8f904249e64bcdb1e38f5a9602df072021-12-02T17:34:30ZMarriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy10.1038/s41467-020-16513-02041-1723https://doaj.org/article/ef8f904249e64bcdb1e38f5a9602df072020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16513-0https://doaj.org/toc/2041-1723A balance between high stability and rapid degradation is required for effective photothermal anti-cancer agents. Here, the authors use Cu2+ to accelerate the degradation of black phosphorus nanosheets while enhancing its photothermal ability and apply this material for PET-guided, CDT-enhanced combination cancer therapy in mice.Kuan HuLin XieYiding ZhangMasayuki HanyuZhimin YangKotaro NagatsuHisashi SuzukiJiang OuyangXiaoyuan JiJunjie WeiHao XuOmid C. FarokhzadSteven H. LiangLu WangWei TaoMing-Rong ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kuan Hu
Lin Xie
Yiding Zhang
Masayuki Hanyu
Zhimin Yang
Kotaro Nagatsu
Hisashi Suzuki
Jiang Ouyang
Xiaoyuan Ji
Junjie Wei
Hao Xu
Omid C. Farokhzad
Steven H. Liang
Lu Wang
Wei Tao
Ming-Rong Zhang
Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy
description A balance between high stability and rapid degradation is required for effective photothermal anti-cancer agents. Here, the authors use Cu2+ to accelerate the degradation of black phosphorus nanosheets while enhancing its photothermal ability and apply this material for PET-guided, CDT-enhanced combination cancer therapy in mice.
format article
author Kuan Hu
Lin Xie
Yiding Zhang
Masayuki Hanyu
Zhimin Yang
Kotaro Nagatsu
Hisashi Suzuki
Jiang Ouyang
Xiaoyuan Ji
Junjie Wei
Hao Xu
Omid C. Farokhzad
Steven H. Liang
Lu Wang
Wei Tao
Ming-Rong Zhang
author_facet Kuan Hu
Lin Xie
Yiding Zhang
Masayuki Hanyu
Zhimin Yang
Kotaro Nagatsu
Hisashi Suzuki
Jiang Ouyang
Xiaoyuan Ji
Junjie Wei
Hao Xu
Omid C. Farokhzad
Steven H. Liang
Lu Wang
Wei Tao
Ming-Rong Zhang
author_sort Kuan Hu
title Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy
title_short Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy
title_full Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy
title_fullStr Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy
title_full_unstemmed Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy
title_sort marriage of black phosphorus and cu2+ as effective photothermal agents for pet-guided combination cancer therapy
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/ef8f904249e64bcdb1e38f5a9602df07
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