Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes

Natsuko Mori,1,2 Hideaki Yokogawa,1 Akira Kobayashi,1 Tsubasa Nishino,1,3 Kazuhisa Sugiyama11Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan; 2Department of Ophthalmology, Saiseikai Kanazawa Hospital, Kanazawa, Japan; 3Department of Ophthalmology,...

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Autores principales:	Mori N, Yokogawa H, Kobayashi A, Nishino T, Sugiyama K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Surgery-induced iris abnormalities DMEK Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/ef902fb715fe4a8fafc5747745b20c4b
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spelling	oai:doaj.org-article:ef902fb715fe4a8fafc5747745b20c4b2021-12-02T08:14:25ZSurgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes1177-5483https://doaj.org/article/ef902fb715fe4a8fafc5747745b20c4b2019-05-01T00:00:00Zhttps://www.dovepress.com/surgery-induced-iris-abnormalities-after-descemet-membrane-endothelial-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Natsuko Mori,1,2 Hideaki Yokogawa,1 Akira Kobayashi,1 Tsubasa Nishino,1,3 Kazuhisa Sugiyama11Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan; 2Department of Ophthalmology, Saiseikai Kanazawa Hospital, Kanazawa, Japan; 3Department of Ophthalmology, Toyama Prefectural Central Hospital, Toyama, JapanPurpose: This study aimed to elucidate the frequency of surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty (DMEK) and their impact on postoperative clinical outcomes.Methods: In this retrospective study, medical records of 32 eyes from 28 consecutive patients (mean age, 65.7±13.4 years; 14 men, 18 women) who underwent DMEK (or triple DMEK) were reviewed. In all patients, inferior peripheral iridectomy was created leaving full intracameral air tamponade at the end of surgery. Sulfur hexafluoride gas was not used in any cases. Surgery-induced iris abnormalities such as pupillary shape changes and iris depigmentation were evaluated by 3 masked observers. Pre-existing abnormalities were excluded. Eyes were divided into two groups based on the presence of surgery-induced iris changes: Group A (with iris abnormalities) and Group B (without). Impacts on postoperative clinical outcomes such as vision and endothelial cell density were analyzed.Results: Surgery-induced iris abnormalities were seen in 15 eyes (Group A, 9 with pupillary shape change and 6 with iris depigmentation; 46.9%), and 17 eyes showed no abnormalities (Group B, 53.1%). No significant differences were detected between groups in age, sex, indication, simultaneous cataract surgery, pre- and 6-month postoperative vision, donor age, donor endothelial cell density, and 6- and 12-month postoperative endothelial cell density.Conclusions: Surgery-induced iris abnormalities were noted in almost half of the eyes after DMEK (46.9%) in this study. However, there was no association between visual outcomes or postoperative endothelial cell density and the iris changes.Keywords: surgery-induced iris abnormalities, DMEKMori NYokogawa HKobayashi ANishino TSugiyama KDove Medical PressarticleSurgery-induced iris abnormalitiesDMEKOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 805-809 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Surgery-induced iris abnormalities DMEK Ophthalmology RE1-994
spellingShingle	Surgery-induced iris abnormalities DMEK Ophthalmology RE1-994 Mori N Yokogawa H Kobayashi A Nishino T Sugiyama K Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes
description	Natsuko Mori,1,2 Hideaki Yokogawa,1 Akira Kobayashi,1 Tsubasa Nishino,1,3 Kazuhisa Sugiyama11Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan; 2Department of Ophthalmology, Saiseikai Kanazawa Hospital, Kanazawa, Japan; 3Department of Ophthalmology, Toyama Prefectural Central Hospital, Toyama, JapanPurpose: This study aimed to elucidate the frequency of surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty (DMEK) and their impact on postoperative clinical outcomes.Methods: In this retrospective study, medical records of 32 eyes from 28 consecutive patients (mean age, 65.7±13.4 years; 14 men, 18 women) who underwent DMEK (or triple DMEK) were reviewed. In all patients, inferior peripheral iridectomy was created leaving full intracameral air tamponade at the end of surgery. Sulfur hexafluoride gas was not used in any cases. Surgery-induced iris abnormalities such as pupillary shape changes and iris depigmentation were evaluated by 3 masked observers. Pre-existing abnormalities were excluded. Eyes were divided into two groups based on the presence of surgery-induced iris changes: Group A (with iris abnormalities) and Group B (without). Impacts on postoperative clinical outcomes such as vision and endothelial cell density were analyzed.Results: Surgery-induced iris abnormalities were seen in 15 eyes (Group A, 9 with pupillary shape change and 6 with iris depigmentation; 46.9%), and 17 eyes showed no abnormalities (Group B, 53.1%). No significant differences were detected between groups in age, sex, indication, simultaneous cataract surgery, pre- and 6-month postoperative vision, donor age, donor endothelial cell density, and 6- and 12-month postoperative endothelial cell density.Conclusions: Surgery-induced iris abnormalities were noted in almost half of the eyes after DMEK (46.9%) in this study. However, there was no association between visual outcomes or postoperative endothelial cell density and the iris changes.Keywords: surgery-induced iris abnormalities, DMEK
format	article
author	Mori N Yokogawa H Kobayashi A Nishino T Sugiyama K
author_facet	Mori N Yokogawa H Kobayashi A Nishino T Sugiyama K
author_sort	Mori N
title	Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes
title_short	Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes
title_full	Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes
title_fullStr	Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes
title_full_unstemmed	Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes
title_sort	surgery-induced iris abnormalities after descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/ef902fb715fe4a8fafc5747745b20c4b
work_keys_str_mv	AT morin surgeryinducedirisabnormalitiesafterdescemetmembraneendothelialkeratoplastyandtheirimpactonpostoperativeclinicaloutcomes AT yokogawah surgeryinducedirisabnormalitiesafterdescemetmembraneendothelialkeratoplastyandtheirimpactonpostoperativeclinicaloutcomes AT kobayashia surgeryinducedirisabnormalitiesafterdescemetmembraneendothelialkeratoplastyandtheirimpactonpostoperativeclinicaloutcomes AT nishinot surgeryinducedirisabnormalitiesafterdescemetmembraneendothelialkeratoplastyandtheirimpactonpostoperativeclinicaloutcomes AT sugiyamak surgeryinducedirisabnormalitiesafterdescemetmembraneendothelialkeratoplastyandtheirimpactonpostoperativeclinicaloutcomes
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Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes

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