Boosting functionality of synthetic DNA circuits with tailored deactivation

Nonlinearity in synthetic molecular circuits is usually achieved by manipulation of network topology or of production kinetics. Here, the authors achieve bistability and other nonlinear behaviours by manipulating the individual degradation rate laws of circuit components using saturable pathways.

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Autores principales:	Kevin Montagne, Guillaume Gines, Teruo Fujii, Yannick Rondelez
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ef972807c48a42ea878801ff6c0110c9
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spelling	oai:doaj.org-article:ef972807c48a42ea878801ff6c0110c92021-12-02T16:57:01ZBoosting functionality of synthetic DNA circuits with tailored deactivation10.1038/ncomms134742041-1723https://doaj.org/article/ef972807c48a42ea878801ff6c0110c92016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13474https://doaj.org/toc/2041-1723Nonlinearity in synthetic molecular circuits is usually achieved by manipulation of network topology or of production kinetics. Here, the authors achieve bistability and other nonlinear behaviours by manipulating the individual degradation rate laws of circuit components using saturable pathways.Kevin MontagneGuillaume GinesTeruo FujiiYannick RondelezNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kevin Montagne Guillaume Gines Teruo Fujii Yannick Rondelez Boosting functionality of synthetic DNA circuits with tailored deactivation
description	Nonlinearity in synthetic molecular circuits is usually achieved by manipulation of network topology or of production kinetics. Here, the authors achieve bistability and other nonlinear behaviours by manipulating the individual degradation rate laws of circuit components using saturable pathways.
format	article
author	Kevin Montagne Guillaume Gines Teruo Fujii Yannick Rondelez
author_facet	Kevin Montagne Guillaume Gines Teruo Fujii Yannick Rondelez
author_sort	Kevin Montagne
title	Boosting functionality of synthetic DNA circuits with tailored deactivation
title_short	Boosting functionality of synthetic DNA circuits with tailored deactivation
title_full	Boosting functionality of synthetic DNA circuits with tailored deactivation
title_fullStr	Boosting functionality of synthetic DNA circuits with tailored deactivation
title_full_unstemmed	Boosting functionality of synthetic DNA circuits with tailored deactivation
title_sort	boosting functionality of synthetic dna circuits with tailored deactivation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/ef972807c48a42ea878801ff6c0110c9
work_keys_str_mv	AT kevinmontagne boostingfunctionalityofsyntheticdnacircuitswithtailoreddeactivation AT guillaumegines boostingfunctionalityofsyntheticdnacircuitswithtailoreddeactivation AT teruofujii boostingfunctionalityofsyntheticdnacircuitswithtailoreddeactivation AT yannickrondelez boostingfunctionalityofsyntheticdnacircuitswithtailoreddeactivation
_version_	1718382656655196160

Boosting functionality of synthetic DNA circuits with tailored deactivation

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