Boosting functionality of synthetic DNA circuits with tailored deactivation

Nonlinearity in synthetic molecular circuits is usually achieved by manipulation of network topology or of production kinetics. Here, the authors achieve bistability and other nonlinear behaviours by manipulating the individual degradation rate laws of circuit components using saturable pathways.

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Auteurs principaux: Kevin Montagne, Guillaume Gines, Teruo Fujii, Yannick Rondelez
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/ef972807c48a42ea878801ff6c0110c9
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