Sublethal doses of diazinon affected reproductive, immune, and oxidative status in female zebrafish (Danio rerio)

Diazion is a common pesticide which cultured fish can be exposed. There is limited information available on the possible effects of diazinon on reproductive parameters of fish. Therefore, in this study, we focused on the effects of sub-lethal doses (0, 0.8, 1.6, and 3.2 mg/L) of diazinon, an organop...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Masoumeh Darvishi, Roghieh Safari, Seyed Hossein Hoseinifar, Ali Shabani, Maryam Dadar, Zahra Jarayedi, Marina Paolucci
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Diazinon Zebrafish Sex hormones Ovary Vitellogenin Estrogen receptor Aquaculture. Fisheries. Angling SH1-691
Acceso en línea:	https://doaj.org/article/ef9a1f0377544b9296d431db464af061
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ef9a1f0377544b9296d431db464af061
record_format	dspace
spelling	oai:doaj.org-article:ef9a1f0377544b9296d431db464af0612021-11-20T05:07:17ZSublethal doses of diazinon affected reproductive, immune, and oxidative status in female zebrafish (Danio rerio)2352-513410.1016/j.aqrep.2021.100944https://doaj.org/article/ef9a1f0377544b9296d431db464af0612022-02-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2352513421003616https://doaj.org/toc/2352-5134Diazion is a common pesticide which cultured fish can be exposed. There is limited information available on the possible effects of diazinon on reproductive parameters of fish. Therefore, in this study, we focused on the effects of sub-lethal doses (0, 0.8, 1.6, and 3.2 mg/L) of diazinon, an organophosphate insecticide on sex hormones, ovarian morphology, reproductive, immunity, and antioxidant related genes, in female zebrafish (Danio rerio) after 30 days of treatment. The expression of reproductive-related genes (CYP19a, Vtg, and ERα) significantly decreased, while the expression of the immune (TNFα and Il-1β) and antioxidant (SOD and CAT) related genes increased considerably. Among sex steroids, only progesterone significantly decreased after the treatment with Diazinon sub-lethal doses, while 17-β estradiol and testosterone did not change. The ovarian morphology showed a decrease in oocyte development in diazinon-treated groups. Understanding the function and mechanism of action of diazinon on the female reproductive, immune, and oxidant status may provide new strategies to counteract its adverse effects.Masoumeh DarvishiRoghieh SafariSeyed Hossein HoseinifarAli ShabaniMaryam DadarZahra JarayediMarina PaolucciElsevierarticleDiazinonZebrafishSex hormonesOvaryVitellogeninEstrogen receptorAquaculture. Fisheries. AnglingSH1-691ENAquaculture Reports, Vol 22, Iss , Pp 100944- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diazinon Zebrafish Sex hormones Ovary Vitellogenin Estrogen receptor Aquaculture. Fisheries. Angling SH1-691
spellingShingle	Diazinon Zebrafish Sex hormones Ovary Vitellogenin Estrogen receptor Aquaculture. Fisheries. Angling SH1-691 Masoumeh Darvishi Roghieh Safari Seyed Hossein Hoseinifar Ali Shabani Maryam Dadar Zahra Jarayedi Marina Paolucci Sublethal doses of diazinon affected reproductive, immune, and oxidative status in female zebrafish (Danio rerio)
description	Diazion is a common pesticide which cultured fish can be exposed. There is limited information available on the possible effects of diazinon on reproductive parameters of fish. Therefore, in this study, we focused on the effects of sub-lethal doses (0, 0.8, 1.6, and 3.2 mg/L) of diazinon, an organophosphate insecticide on sex hormones, ovarian morphology, reproductive, immunity, and antioxidant related genes, in female zebrafish (Danio rerio) after 30 days of treatment. The expression of reproductive-related genes (CYP19a, Vtg, and ERα) significantly decreased, while the expression of the immune (TNFα and Il-1β) and antioxidant (SOD and CAT) related genes increased considerably. Among sex steroids, only progesterone significantly decreased after the treatment with Diazinon sub-lethal doses, while 17-β estradiol and testosterone did not change. The ovarian morphology showed a decrease in oocyte development in diazinon-treated groups. Understanding the function and mechanism of action of diazinon on the female reproductive, immune, and oxidant status may provide new strategies to counteract its adverse effects.
format	article
author	Masoumeh Darvishi Roghieh Safari Seyed Hossein Hoseinifar Ali Shabani Maryam Dadar Zahra Jarayedi Marina Paolucci
author_facet	Masoumeh Darvishi Roghieh Safari Seyed Hossein Hoseinifar Ali Shabani Maryam Dadar Zahra Jarayedi Marina Paolucci
author_sort	Masoumeh Darvishi
title	Sublethal doses of diazinon affected reproductive, immune, and oxidative status in female zebrafish (Danio rerio)
title_short	Sublethal doses of diazinon affected reproductive, immune, and oxidative status in female zebrafish (Danio rerio)
title_full	Sublethal doses of diazinon affected reproductive, immune, and oxidative status in female zebrafish (Danio rerio)
title_fullStr	Sublethal doses of diazinon affected reproductive, immune, and oxidative status in female zebrafish (Danio rerio)
title_full_unstemmed	Sublethal doses of diazinon affected reproductive, immune, and oxidative status in female zebrafish (Danio rerio)
title_sort	sublethal doses of diazinon affected reproductive, immune, and oxidative status in female zebrafish (danio rerio)
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/ef9a1f0377544b9296d431db464af061
work_keys_str_mv	AT masoumehdarvishi sublethaldosesofdiazinonaffectedreproductiveimmuneandoxidativestatusinfemalezebrafishdaniorerio AT roghiehsafari sublethaldosesofdiazinonaffectedreproductiveimmuneandoxidativestatusinfemalezebrafishdaniorerio AT seyedhosseinhoseinifar sublethaldosesofdiazinonaffectedreproductiveimmuneandoxidativestatusinfemalezebrafishdaniorerio AT alishabani sublethaldosesofdiazinonaffectedreproductiveimmuneandoxidativestatusinfemalezebrafishdaniorerio AT maryamdadar sublethaldosesofdiazinonaffectedreproductiveimmuneandoxidativestatusinfemalezebrafishdaniorerio AT zahrajarayedi sublethaldosesofdiazinonaffectedreproductiveimmuneandoxidativestatusinfemalezebrafishdaniorerio AT marinapaolucci sublethaldosesofdiazinonaffectedreproductiveimmuneandoxidativestatusinfemalezebrafishdaniorerio
_version_	1718419575292297216

Sublethal doses of diazinon affected reproductive, immune, and oxidative status in female zebrafish (Danio rerio)

Ejemplares similares