Thrombin Cleavage of <named-content content-type="genus-species">Plasmodium falciparum</named-content> Erythrocyte Membrane Protein 1 Inhibits Cytoadherence

Thrombin Cleavage of <named-content content-type="genus-species">Plasmodium falciparum</named-content> Erythrocyte Membrane Protein 1 Inhibits Cytoadherence

ABSTRACT Plasmodium falciparum malaria remains one of the most deadly infections worldwide. The pathogenesis of the infection results from the sequestration of infected erythrocytes (IRBC) in vital organs, including the brain, with resulting impairment of blood flow, hypoxia, and lactic acidosis. Se...

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Autores principales: Mark R. Gillrie, Bernard Renaux, Eleanor Russell-Goldman, Marion Avril, Andrew J. Brazier, Koichiro Mihara, Enrico Di Cera, Danny A. Milner, Morley D. Hollenberg, Joseph D. Smith, May Ho
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/ef9c28ad329b4fbba481ab5d041f6224
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