Mucosal vaccination with pili from Group A Streptococcus expressed on Lactococcus lactis generates protective immune responses

Mucosal vaccination with pili from Group A Streptococcus expressed on Lactococcus lactis generates protective immune responses

Abstract The human pathogen Group A Streptococcus (GAS) produces pili that are involved in adhesion and colonisation of the host. These surface-exposed pili are immunogenic and therefore represent an attractive target for vaccine development. The pilus is encoded in the genomic region known as the f...

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Autores principales: Jacelyn M. S. Loh, Natalie Lorenz, Catherine J.-Y. Tsai, Adrina Hema J. Khemlani, Thomas Proft
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/efa58e577bca4160909851cb9564e2f3
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