Influencing factors of noninvasive positive pressure ventilation in the treatment of respiratory failure: a 10-year study in one single center

Abstract Background The utilization of noninvasive positive pressure ventilation (NPPV) is becoming more and more common, especially in patients with acute or chronic respiratory failure. The purpose of our study is to analyze the factors that influence the efficacy of NPPV in the treatment of respi...

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Autores principales:	Juan Wang, Shuang Bian, Xiaomiao Tang, Sheng Ye, Shen Meng, Wei Lei
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Noninvasive positive pressure ventilation Respiratory failure Influencing factors Medicine R
Acceso en línea:	https://doaj.org/article/efb0686e1fbe49f6af43ddf8bb496a0d
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spelling	oai:doaj.org-article:efb0686e1fbe49f6af43ddf8bb496a0d2021-12-05T12:17:42ZInfluencing factors of noninvasive positive pressure ventilation in the treatment of respiratory failure: a 10-year study in one single center10.1186/s40001-021-00615-62047-783Xhttps://doaj.org/article/efb0686e1fbe49f6af43ddf8bb496a0d2021-12-01T00:00:00Zhttps://doi.org/10.1186/s40001-021-00615-6https://doaj.org/toc/2047-783XAbstract Background The utilization of noninvasive positive pressure ventilation (NPPV) is becoming more and more common, especially in patients with acute or chronic respiratory failure. The purpose of our study is to analyze the factors that influence the efficacy of NPPV in the treatment of respiratory failure caused by a variety of etiology. Methods From May 2011 to April 2020, patients treated with NPPV during hospitalization in the First Affiliated Hospital of Soochow University were enrolled. According to the clinical outcome of NPPV treatment and whether converted to invasive mechanical ventilation, patients were divided into the success group and the failure group. The clinical data and the characteristics of NPPV application were compared between the two groups. Results A total of 3312 patients were enrolled, including 2025 patients in the success group and 1287 patients in the failure group. Univariate analysis suggested that there were no statistical differences in patients' age, gender, use of analgesia and/or sedation, complicated with barotrauma, inspiratory positive airway pressure and expiratory positive airway pressure between the success and failure groups (P > 0.05). However, there were statistically significant differences in serum albumin levels, Ca2+ concentration, blood glucose levels, duration of NPPV treatment and length of hospital stay between the success and failure groups (P < 0.05). Multivariate logistic regression analysis indicated that serum albumin levels and duration of NPPV treatment had statistical significance on the therapeutic effect of NPPV (P < 0.05). Conclusion Serum albumin levels and duration of NPPV treatment were independent risk factors for the efficacy of NPPV treatment in respiratory failure.Juan WangShuang BianXiaomiao TangSheng YeShen MengWei LeiBMCarticleNoninvasive positive pressure ventilationRespiratory failureInfluencing factorsMedicineRENEuropean Journal of Medical Research, Vol 26, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Noninvasive positive pressure ventilation Respiratory failure Influencing factors Medicine R
spellingShingle	Noninvasive positive pressure ventilation Respiratory failure Influencing factors Medicine R Juan Wang Shuang Bian Xiaomiao Tang Sheng Ye Shen Meng Wei Lei Influencing factors of noninvasive positive pressure ventilation in the treatment of respiratory failure: a 10-year study in one single center
description	Abstract Background The utilization of noninvasive positive pressure ventilation (NPPV) is becoming more and more common, especially in patients with acute or chronic respiratory failure. The purpose of our study is to analyze the factors that influence the efficacy of NPPV in the treatment of respiratory failure caused by a variety of etiology. Methods From May 2011 to April 2020, patients treated with NPPV during hospitalization in the First Affiliated Hospital of Soochow University were enrolled. According to the clinical outcome of NPPV treatment and whether converted to invasive mechanical ventilation, patients were divided into the success group and the failure group. The clinical data and the characteristics of NPPV application were compared between the two groups. Results A total of 3312 patients were enrolled, including 2025 patients in the success group and 1287 patients in the failure group. Univariate analysis suggested that there were no statistical differences in patients' age, gender, use of analgesia and/or sedation, complicated with barotrauma, inspiratory positive airway pressure and expiratory positive airway pressure between the success and failure groups (P > 0.05). However, there were statistically significant differences in serum albumin levels, Ca2+ concentration, blood glucose levels, duration of NPPV treatment and length of hospital stay between the success and failure groups (P < 0.05). Multivariate logistic regression analysis indicated that serum albumin levels and duration of NPPV treatment had statistical significance on the therapeutic effect of NPPV (P < 0.05). Conclusion Serum albumin levels and duration of NPPV treatment were independent risk factors for the efficacy of NPPV treatment in respiratory failure.
format	article
author	Juan Wang Shuang Bian Xiaomiao Tang Sheng Ye Shen Meng Wei Lei
author_facet	Juan Wang Shuang Bian Xiaomiao Tang Sheng Ye Shen Meng Wei Lei
author_sort	Juan Wang
title	Influencing factors of noninvasive positive pressure ventilation in the treatment of respiratory failure: a 10-year study in one single center
title_short	Influencing factors of noninvasive positive pressure ventilation in the treatment of respiratory failure: a 10-year study in one single center
title_full	Influencing factors of noninvasive positive pressure ventilation in the treatment of respiratory failure: a 10-year study in one single center
title_fullStr	Influencing factors of noninvasive positive pressure ventilation in the treatment of respiratory failure: a 10-year study in one single center
title_full_unstemmed	Influencing factors of noninvasive positive pressure ventilation in the treatment of respiratory failure: a 10-year study in one single center
title_sort	influencing factors of noninvasive positive pressure ventilation in the treatment of respiratory failure: a 10-year study in one single center
publisher	BMC
publishDate	2021
url	https://doaj.org/article/efb0686e1fbe49f6af43ddf8bb496a0d
work_keys_str_mv	AT juanwang influencingfactorsofnoninvasivepositivepressureventilationinthetreatmentofrespiratoryfailurea10yearstudyinonesinglecenter AT shuangbian influencingfactorsofnoninvasivepositivepressureventilationinthetreatmentofrespiratoryfailurea10yearstudyinonesinglecenter AT xiaomiaotang influencingfactorsofnoninvasivepositivepressureventilationinthetreatmentofrespiratoryfailurea10yearstudyinonesinglecenter AT shengye influencingfactorsofnoninvasivepositivepressureventilationinthetreatmentofrespiratoryfailurea10yearstudyinonesinglecenter AT shenmeng influencingfactorsofnoninvasivepositivepressureventilationinthetreatmentofrespiratoryfailurea10yearstudyinonesinglecenter AT weilei influencingfactorsofnoninvasivepositivepressureventilationinthetreatmentofrespiratoryfailurea10yearstudyinonesinglecenter
_version_	1718372110035845120

Influencing factors of noninvasive positive pressure ventilation in the treatment of respiratory failure: a 10-year study in one single center

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