Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity

Peptide-based supramolecular assemblies are a promising class of nanomaterials with important biomedical applications, but their antibacterial properties can be overlooked. Here the authors show the antibacterial activity of self-assembled diphenylalanine, which emerges as the minimal model for anti...

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Autores principales: Lee Schnaider, Sayanti Brahmachari, Nathan W. Schmidt, Bruk Mensa, Shira Shaham-Niv, Darya Bychenko, Lihi Adler-Abramovich, Linda J. W. Shimon, Sofiya Kolusheva, William F. DeGrado, Ehud Gazit
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/efb41b995bd74dbab61d3ed3bd64f959
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spelling oai:doaj.org-article:efb41b995bd74dbab61d3ed3bd64f9592021-12-02T17:06:06ZSelf-assembling dipeptide antibacterial nanostructures with membrane disrupting activity10.1038/s41467-017-01447-x2041-1723https://doaj.org/article/efb41b995bd74dbab61d3ed3bd64f9592017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01447-xhttps://doaj.org/toc/2041-1723Peptide-based supramolecular assemblies are a promising class of nanomaterials with important biomedical applications, but their antibacterial properties can be overlooked. Here the authors show the antibacterial activity of self-assembled diphenylalanine, which emerges as the minimal model for antibacterial supramolecular polymers.Lee SchnaiderSayanti BrahmachariNathan W. SchmidtBruk MensaShira Shaham-NivDarya BychenkoLihi Adler-AbramovichLinda J. W. ShimonSofiya KolushevaWilliam F. DeGradoEhud GazitNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lee Schnaider
Sayanti Brahmachari
Nathan W. Schmidt
Bruk Mensa
Shira Shaham-Niv
Darya Bychenko
Lihi Adler-Abramovich
Linda J. W. Shimon
Sofiya Kolusheva
William F. DeGrado
Ehud Gazit
Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity
description Peptide-based supramolecular assemblies are a promising class of nanomaterials with important biomedical applications, but their antibacterial properties can be overlooked. Here the authors show the antibacterial activity of self-assembled diphenylalanine, which emerges as the minimal model for antibacterial supramolecular polymers.
format article
author Lee Schnaider
Sayanti Brahmachari
Nathan W. Schmidt
Bruk Mensa
Shira Shaham-Niv
Darya Bychenko
Lihi Adler-Abramovich
Linda J. W. Shimon
Sofiya Kolusheva
William F. DeGrado
Ehud Gazit
author_facet Lee Schnaider
Sayanti Brahmachari
Nathan W. Schmidt
Bruk Mensa
Shira Shaham-Niv
Darya Bychenko
Lihi Adler-Abramovich
Linda J. W. Shimon
Sofiya Kolusheva
William F. DeGrado
Ehud Gazit
author_sort Lee Schnaider
title Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity
title_short Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity
title_full Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity
title_fullStr Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity
title_full_unstemmed Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity
title_sort self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/efb41b995bd74dbab61d3ed3bd64f959
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