CRISPR-Associated Primase-Polymerases are implicated in prokaryotic CRISPR-Cas adaptation

CAPPs are putative Primase-Polymerases associated with CRISPR-Cas operons. Here, the authors show CAPPs genetic and physical association with Cas1 and Cas2, their capacity to function as DNA-dependent DNA primases and DNA polymerases, and that Cas1-Cas2 complex adjacent to CAPP has bona fide spacer...

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Bibliographic Details
Main Authors: Katerina Zabrady, Matej Zabrady, Peter Kolesar, Arthur W. H. Li, Aidan J. Doherty
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/efc9c689cc494105b57df2aab55a9b23
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