Moderate alcohol use and mortality from ischaemic heart disease: a prospective study in older Chinese people.

<h4>Background</h4>Moderate alcohol use is generally associated with lower ischaemic heart disease (IHD) mortality but it is difficult to ascertain whether this is due to attributes of moderate alcohol users or the properties of alcohol itself. Evidence from populations with different pa...

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Autores principales:	C Mary Schooling, Wenjie Sun, Sai Yin Ho, Wai Man Chan, May Ked Tham, Kin Sang Ho, Gabriel M Leung, Tai Hing Lam
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2008
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/efd21499dce24ead9ce95625e44eb291
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spelling	oai:doaj.org-article:efd21499dce24ead9ce95625e44eb2912021-11-25T06:12:10ZModerate alcohol use and mortality from ischaemic heart disease: a prospective study in older Chinese people.1932-620310.1371/journal.pone.0002370https://doaj.org/article/efd21499dce24ead9ce95625e44eb2912008-06-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18523644/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Moderate alcohol use is generally associated with lower ischaemic heart disease (IHD) mortality but it is difficult to ascertain whether this is due to attributes of moderate alcohol users or the properties of alcohol itself. Evidence from populations with different patterns of alcohol use and IHD can provide crucial evidence. We assessed the association of moderate alcohol use with IHD mortality in older Chinese people from Hong Kong.<h4>Methodology</h4>We used Cox regression to determine whether moderate alcohol use was associated with IHD mortality in a prospective, population-based cohort study of all 56,167 attendees, aged 65 years or over, from July 1998 to December 2000 at all 18 Elderly Health Centers operated by the Department of Health in Hong Kong.<h4>Principal findings</h4>After a median follow-up of 4.2 years, there were 406 (188 in men, 218 in women) deaths from IHD in 54,090 subjects (96.3% successful follow-up). Moderate alcohol use in men was not associated with IHD mortality adjusted only for age [Hazard Ratio, HR 1.01 (95% CI 0.55 to 1.84) compared with never drinkers] or additionally adjusted for socio-economic status and lifestyle. Almost all women were occasional drinkers and their current alcohol use was not significantly associated with IHD mortality [HR 0.88, (95% CI 0.51 to 1.53)].<h4>Conclusions</h4>Moderate alcohol use had no effect on IHD mortality in older Chinese men. Lack of replication of the usual protective effect of moderate alcohol use in a setting with a different pattern of alcohol use and IHD could be due to chance or could suggest that the protective effect of alcohol on IHD does not extend to all populations.C Mary SchoolingWenjie SunSai Yin HoWai Man ChanMay Ked ThamKin Sang HoGabriel M LeungTai Hing LamPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 3, Iss 6, p e2370 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q C Mary Schooling Wenjie Sun Sai Yin Ho Wai Man Chan May Ked Tham Kin Sang Ho Gabriel M Leung Tai Hing Lam Moderate alcohol use and mortality from ischaemic heart disease: a prospective study in older Chinese people.
description	<h4>Background</h4>Moderate alcohol use is generally associated with lower ischaemic heart disease (IHD) mortality but it is difficult to ascertain whether this is due to attributes of moderate alcohol users or the properties of alcohol itself. Evidence from populations with different patterns of alcohol use and IHD can provide crucial evidence. We assessed the association of moderate alcohol use with IHD mortality in older Chinese people from Hong Kong.<h4>Methodology</h4>We used Cox regression to determine whether moderate alcohol use was associated with IHD mortality in a prospective, population-based cohort study of all 56,167 attendees, aged 65 years or over, from July 1998 to December 2000 at all 18 Elderly Health Centers operated by the Department of Health in Hong Kong.<h4>Principal findings</h4>After a median follow-up of 4.2 years, there were 406 (188 in men, 218 in women) deaths from IHD in 54,090 subjects (96.3% successful follow-up). Moderate alcohol use in men was not associated with IHD mortality adjusted only for age [Hazard Ratio, HR 1.01 (95% CI 0.55 to 1.84) compared with never drinkers] or additionally adjusted for socio-economic status and lifestyle. Almost all women were occasional drinkers and their current alcohol use was not significantly associated with IHD mortality [HR 0.88, (95% CI 0.51 to 1.53)].<h4>Conclusions</h4>Moderate alcohol use had no effect on IHD mortality in older Chinese men. Lack of replication of the usual protective effect of moderate alcohol use in a setting with a different pattern of alcohol use and IHD could be due to chance or could suggest that the protective effect of alcohol on IHD does not extend to all populations.
format	article
author	C Mary Schooling Wenjie Sun Sai Yin Ho Wai Man Chan May Ked Tham Kin Sang Ho Gabriel M Leung Tai Hing Lam
author_facet	C Mary Schooling Wenjie Sun Sai Yin Ho Wai Man Chan May Ked Tham Kin Sang Ho Gabriel M Leung Tai Hing Lam
author_sort	C Mary Schooling
title	Moderate alcohol use and mortality from ischaemic heart disease: a prospective study in older Chinese people.
title_short	Moderate alcohol use and mortality from ischaemic heart disease: a prospective study in older Chinese people.
title_full	Moderate alcohol use and mortality from ischaemic heart disease: a prospective study in older Chinese people.
title_fullStr	Moderate alcohol use and mortality from ischaemic heart disease: a prospective study in older Chinese people.
title_full_unstemmed	Moderate alcohol use and mortality from ischaemic heart disease: a prospective study in older Chinese people.
title_sort	moderate alcohol use and mortality from ischaemic heart disease: a prospective study in older chinese people.
publisher	Public Library of Science (PLoS)
publishDate	2008
url	https://doaj.org/article/efd21499dce24ead9ce95625e44eb291
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Moderate alcohol use and mortality from ischaemic heart disease: a prospective study in older Chinese people.

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