INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers

INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers

Chromatin remodellers usually mobilize or disassemble nucleosomes by translocating along the nucleosomal DNA at the H3-H4 interface. Here, the authors provide evidence chromatin remodeller INO80 translocates along DNA at the H2A-H2B interface and displaces DNA from the surface of H2A-H2B.

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Detalles Bibliográficos
Autores principales: Sandipan Brahma, Maheshi I. Udugama, Jongseong Kim, Arjan Hada, Saurabh K. Bhardwaj, Solomon G. Hailu, Tae-Hee Lee, Blaine Bartholomew
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
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Acceso en línea:https://doaj.org/article/efde14d4e3754f9bbcffa95733e77a87
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