Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response

ABSTRACT The necessity of viruses to modulate the innate immune response often dictates the outcome of viral infection. As such, viruses encode many factors that undermine these potent antiviral responses. A recent study by Bouvet et al. (M. Bouvet, S. Voigt, T. Tagawa, M. Albanese, et al., mBio 12:...

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Autor principal:	Eain A. Murphy
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	EBV interferon miRNA ncRNA pDCs Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/efe6a716fd994527b6ecd46d65fe125f
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spelling	oai:doaj.org-article:efe6a716fd994527b6ecd46d65fe125f2021-11-10T18:37:52ZReevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response10.1128/mBio.00700-212150-7511https://doaj.org/article/efe6a716fd994527b6ecd46d65fe125f2021-08-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00700-21https://doaj.org/toc/2150-7511ABSTRACT The necessity of viruses to modulate the innate immune response often dictates the outcome of viral infection. As such, viruses encode many factors that undermine these potent antiviral responses. A recent study by Bouvet et al. (M. Bouvet, S. Voigt, T. Tagawa, M. Albanese, et al., mBio 12:e03440-20, 2021, https://doi.org/10.1128/mBio.03440-20) revisits the impact of virus-encoded noncoding RNAs on key components of the interferon pathway and sheds light on how the extensive biological functions of Epstein-Barr virus (EBV) microRNAs (miRNAs) are on targeting both the induction and signaling cascades of interferon.Eain A. MurphyAmerican Society for MicrobiologyarticleEBVinterferonmiRNAncRNApDCsMicrobiologyQR1-502ENmBio, Vol 12, Iss 4 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	EBV interferon miRNA ncRNA pDCs Microbiology QR1-502
spellingShingle	EBV interferon miRNA ncRNA pDCs Microbiology QR1-502 Eain A. Murphy Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
description	ABSTRACT The necessity of viruses to modulate the innate immune response often dictates the outcome of viral infection. As such, viruses encode many factors that undermine these potent antiviral responses. A recent study by Bouvet et al. (M. Bouvet, S. Voigt, T. Tagawa, M. Albanese, et al., mBio 12:e03440-20, 2021, https://doi.org/10.1128/mBio.03440-20) revisits the impact of virus-encoded noncoding RNAs on key components of the interferon pathway and sheds light on how the extensive biological functions of Epstein-Barr virus (EBV) microRNAs (miRNAs) are on targeting both the induction and signaling cascades of interferon.
format	article
author	Eain A. Murphy
author_facet	Eain A. Murphy
author_sort	Eain A. Murphy
title	Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_short	Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_full	Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_fullStr	Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_full_unstemmed	Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_sort	reevaluating the impact of epstein-barr virus noncoding rnas on the interferon response
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/efe6a716fd994527b6ecd46d65fe125f
work_keys_str_mv	AT eainamurphy reevaluatingtheimpactofepsteinbarrvirusnoncodingrnasontheinterferonresponse
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Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response

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