Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response

ABSTRACT The necessity of viruses to modulate the innate immune response often dictates the outcome of viral infection. As such, viruses encode many factors that undermine these potent antiviral responses. A recent study by Bouvet et al. (M. Bouvet, S. Voigt, T. Tagawa, M. Albanese, et al., mBio 12:...

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Autor principal: Eain A. Murphy
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
EBV
Acceso en línea:https://doaj.org/article/efe6a716fd994527b6ecd46d65fe125f
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spelling oai:doaj.org-article:efe6a716fd994527b6ecd46d65fe125f2021-11-10T18:37:52ZReevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response10.1128/mBio.00700-212150-7511https://doaj.org/article/efe6a716fd994527b6ecd46d65fe125f2021-08-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00700-21https://doaj.org/toc/2150-7511ABSTRACT The necessity of viruses to modulate the innate immune response often dictates the outcome of viral infection. As such, viruses encode many factors that undermine these potent antiviral responses. A recent study by Bouvet et al. (M. Bouvet, S. Voigt, T. Tagawa, M. Albanese, et al., mBio 12:e03440-20, 2021, https://doi.org/10.1128/mBio.03440-20) revisits the impact of virus-encoded noncoding RNAs on key components of the interferon pathway and sheds light on how the extensive biological functions of Epstein-Barr virus (EBV) microRNAs (miRNAs) are on targeting both the induction and signaling cascades of interferon.Eain A. MurphyAmerican Society for MicrobiologyarticleEBVinterferonmiRNAncRNApDCsMicrobiologyQR1-502ENmBio, Vol 12, Iss 4 (2021)
institution DOAJ
collection DOAJ
language EN
topic EBV
interferon
miRNA
ncRNA
pDCs
Microbiology
QR1-502
spellingShingle EBV
interferon
miRNA
ncRNA
pDCs
Microbiology
QR1-502
Eain A. Murphy
Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
description ABSTRACT The necessity of viruses to modulate the innate immune response often dictates the outcome of viral infection. As such, viruses encode many factors that undermine these potent antiviral responses. A recent study by Bouvet et al. (M. Bouvet, S. Voigt, T. Tagawa, M. Albanese, et al., mBio 12:e03440-20, 2021, https://doi.org/10.1128/mBio.03440-20) revisits the impact of virus-encoded noncoding RNAs on key components of the interferon pathway and sheds light on how the extensive biological functions of Epstein-Barr virus (EBV) microRNAs (miRNAs) are on targeting both the induction and signaling cascades of interferon.
format article
author Eain A. Murphy
author_facet Eain A. Murphy
author_sort Eain A. Murphy
title Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_short Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_full Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_fullStr Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_full_unstemmed Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
title_sort reevaluating the impact of epstein-barr virus noncoding rnas on the interferon response
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/efe6a716fd994527b6ecd46d65fe125f
work_keys_str_mv AT eainamurphy reevaluatingtheimpactofepsteinbarrvirusnoncodingrnasontheinterferonresponse
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