Emergence of resonances in neural systems: the interplay between adaptive threshold and short-term synaptic plasticity.

In this work we study the detection of weak stimuli by spiking (integrate-and-fire) neurons in the presence of certain level of noisy background neural activity. Our study has focused in the realistic assumption that the synapses in the network present activity-dependent processes, such as short-ter...

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Autores principales:	Jorge F Mejias, Joaquin J Torres
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/eff34e89fc4644c98448fca8c305fa6a
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spelling	oai:doaj.org-article:eff34e89fc4644c98448fca8c305fa6a2021-11-18T06:57:38ZEmergence of resonances in neural systems: the interplay between adaptive threshold and short-term synaptic plasticity.1932-620310.1371/journal.pone.0017255https://doaj.org/article/eff34e89fc4644c98448fca8c305fa6a2011-03-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21408148/?tool=EBIhttps://doaj.org/toc/1932-6203In this work we study the detection of weak stimuli by spiking (integrate-and-fire) neurons in the presence of certain level of noisy background neural activity. Our study has focused in the realistic assumption that the synapses in the network present activity-dependent processes, such as short-term synaptic depression and facilitation. Employing mean-field techniques as well as numerical simulations, we found that there are two possible noise levels which optimize signal transmission. This new finding is in contrast with the classical theory of stochastic resonance which is able to predict only one optimal level of noise. We found that the complex interplay between adaptive neuron threshold and activity-dependent synaptic mechanisms is responsible for this new phenomenology. Our main results are confirmed by employing a more realistic FitzHugh-Nagumo neuron model, which displays threshold variability, as well as by considering more realistic stochastic synaptic models and realistic signals such as poissonian spike trains.Jorge F MejiasJoaquin J TorresPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 3, p e17255 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jorge F Mejias Joaquin J Torres Emergence of resonances in neural systems: the interplay between adaptive threshold and short-term synaptic plasticity.
description	In this work we study the detection of weak stimuli by spiking (integrate-and-fire) neurons in the presence of certain level of noisy background neural activity. Our study has focused in the realistic assumption that the synapses in the network present activity-dependent processes, such as short-term synaptic depression and facilitation. Employing mean-field techniques as well as numerical simulations, we found that there are two possible noise levels which optimize signal transmission. This new finding is in contrast with the classical theory of stochastic resonance which is able to predict only one optimal level of noise. We found that the complex interplay between adaptive neuron threshold and activity-dependent synaptic mechanisms is responsible for this new phenomenology. Our main results are confirmed by employing a more realistic FitzHugh-Nagumo neuron model, which displays threshold variability, as well as by considering more realistic stochastic synaptic models and realistic signals such as poissonian spike trains.
format	article
author	Jorge F Mejias Joaquin J Torres
author_facet	Jorge F Mejias Joaquin J Torres
author_sort	Jorge F Mejias
title	Emergence of resonances in neural systems: the interplay between adaptive threshold and short-term synaptic plasticity.
title_short	Emergence of resonances in neural systems: the interplay between adaptive threshold and short-term synaptic plasticity.
title_full	Emergence of resonances in neural systems: the interplay between adaptive threshold and short-term synaptic plasticity.
title_fullStr	Emergence of resonances in neural systems: the interplay between adaptive threshold and short-term synaptic plasticity.
title_full_unstemmed	Emergence of resonances in neural systems: the interplay between adaptive threshold and short-term synaptic plasticity.
title_sort	emergence of resonances in neural systems: the interplay between adaptive threshold and short-term synaptic plasticity.
publisher	Public Library of Science (PLoS)
publishDate	2011
url	https://doaj.org/article/eff34e89fc4644c98448fca8c305fa6a
work_keys_str_mv	AT jorgefmejias emergenceofresonancesinneuralsystemstheinterplaybetweenadaptivethresholdandshorttermsynapticplasticity AT joaquinjtorres emergenceofresonancesinneuralsystemstheinterplaybetweenadaptivethresholdandshorttermsynapticplasticity
_version_	1718424204508921856

Emergence of resonances in neural systems: the interplay between adaptive threshold and short-term synaptic plasticity.

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