β-Lactam Antibiotics Enhance the Pathogenicity of Methicillin-Resistant <named-content content-type="genus-species">Staphylococcus aureus</named-content> via SarA-Controlled Lipoprotein-Like Cluster Expression

β-Lactam Antibiotics Enhance the Pathogenicity of Methicillin-Resistant <named-content content-type="genus-species">Staphylococcus aureus</named-content> via SarA-Controlled Lipoprotein-Like Cluster Expression

ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) resists nearly all β-lactam antibiotics that have a bactericidal activity. However, whether the empirically used β-lactams enhance MRSA pathogenicity in vivo remains unclear. In this study, we showed that a cluster of lipoprotein-like genes...

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Bibliographic Details
Main Authors: Weilong Shang, Yifan Rao, Ying Zheng, Yi Yang, Qiwen Hu, Zhen Hu, Jizhen Yuan, Huagang Peng, Kun Xiong, Li Tan, Shu Li, Junmin Zhu, Ming Li, Xiaomei Hu, Xuhu Mao, Xiancai Rao
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
β-lactam antibiotics
methicillin-resistant Staphylococcus aureus
SarA
TLR2
lipoprotein-like genes
pathogenicity
Microbiology
QR1-502
Online Access:https://doaj.org/article/eff6ce4468ec480f80be91e27f583649
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https://doaj.org/article/eff6ce4468ec480f80be91e27f583649

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