Mammarenaviruses of Rodents, South Africa and Zimbabwe
We conducted a survey for group-specific indirect immunofluorescence antibody to mammarenaviruses by using Lassa fever and Mopeia virus antigens on serum specimens of 5,363 rodents of 33 species collected in South Africa and Zimbabwe during 1964–1994. Rodents were collected for unrelated purposes o...
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Centers for Disease Control and Prevention
2021
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oai:doaj.org-article:f0017e9d5d4941b1826503127913b7fc2021-11-22T12:57:25ZMammarenaviruses of Rodents, South Africa and Zimbabwe10.3201/eid2712.2110881080-60401080-6059https://doaj.org/article/f0017e9d5d4941b1826503127913b7fc2021-12-01T00:00:00Zhttps://wwwnc.cdc.gov/eid/article/27/12/21-1088_articlehttps://doaj.org/toc/1080-6040https://doaj.org/toc/1080-6059 We conducted a survey for group-specific indirect immunofluorescence antibody to mammarenaviruses by using Lassa fever and Mopeia virus antigens on serum specimens of 5,363 rodents of 33 species collected in South Africa and Zimbabwe during 1964–1994. Rodents were collected for unrelated purposes or for this study and stored at −70°C. We found antibody to be widely distributed in the 2 countries; antibody was detected in serum specimens of 1.2%–31.8% of 14 species of myomorph rodents, whereas 19 mammarenavirus isolates were obtained from serum specimens and viscera of 4 seropositive species. Phylogenetic analysis on the basis of partial nucleoprotein sequences indicates that 14 isolates from Mastomys natalensis, the Natal multimammate mouse, were Mopeia virus, whereas Merino Walk virus was characterized as a novel virus in a separate study. The remaining 4 isolates from 3 rodent species potentially constitute novel viruses pending full characterization. Antoinette A. GrobbelaarJocelyn JardineFelicity J. BurtAlasdair J. ShepherdSusan P. ShepherdPatricia A. LemanAlan KempLawrence E.O. BraackJacqueline WeyerJanusz T. PaweskaRobert SwanepoelCenters for Disease Control and PreventionarticlemammarenavirusSouth AfricaZimbabweMastomys natalensisMopeia virusvirusesMedicineRInfectious and parasitic diseasesRC109-216ENEmerging Infectious Diseases, Vol 27, Iss 12, Pp 3092-3102 (2021) |
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DOAJ |
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EN |
| topic |
mammarenavirus South Africa Zimbabwe Mastomys natalensis Mopeia virus viruses Medicine R Infectious and parasitic diseases RC109-216 |
| spellingShingle |
mammarenavirus South Africa Zimbabwe Mastomys natalensis Mopeia virus viruses Medicine R Infectious and parasitic diseases RC109-216 Antoinette A. Grobbelaar Jocelyn Jardine Felicity J. Burt Alasdair J. Shepherd Susan P. Shepherd Patricia A. Leman Alan Kemp Lawrence E.O. Braack Jacqueline Weyer Janusz T. Paweska Robert Swanepoel Mammarenaviruses of Rodents, South Africa and Zimbabwe |
| description |
We conducted a survey for group-specific indirect immunofluorescence antibody to mammarenaviruses by using Lassa fever and Mopeia virus antigens on serum specimens of 5,363 rodents of 33 species collected in South Africa and Zimbabwe during 1964–1994. Rodents were collected for unrelated purposes or for this study and stored at −70°C. We found antibody to be widely distributed in the 2 countries; antibody was detected in serum specimens of 1.2%–31.8% of 14 species of myomorph rodents, whereas 19 mammarenavirus isolates were obtained from serum specimens and viscera of 4 seropositive species. Phylogenetic analysis on the basis of partial nucleoprotein sequences indicates that 14 isolates from Mastomys natalensis, the Natal multimammate mouse, were Mopeia virus, whereas Merino Walk virus was characterized as a novel virus in a separate study. The remaining 4 isolates from 3 rodent species potentially constitute novel viruses pending full characterization.
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| format |
article |
| author |
Antoinette A. Grobbelaar Jocelyn Jardine Felicity J. Burt Alasdair J. Shepherd Susan P. Shepherd Patricia A. Leman Alan Kemp Lawrence E.O. Braack Jacqueline Weyer Janusz T. Paweska Robert Swanepoel |
| author_facet |
Antoinette A. Grobbelaar Jocelyn Jardine Felicity J. Burt Alasdair J. Shepherd Susan P. Shepherd Patricia A. Leman Alan Kemp Lawrence E.O. Braack Jacqueline Weyer Janusz T. Paweska Robert Swanepoel |
| author_sort |
Antoinette A. Grobbelaar |
| title |
Mammarenaviruses of Rodents, South Africa and Zimbabwe |
| title_short |
Mammarenaviruses of Rodents, South Africa and Zimbabwe |
| title_full |
Mammarenaviruses of Rodents, South Africa and Zimbabwe |
| title_fullStr |
Mammarenaviruses of Rodents, South Africa and Zimbabwe |
| title_full_unstemmed |
Mammarenaviruses of Rodents, South Africa and Zimbabwe |
| title_sort |
mammarenaviruses of rodents, south africa and zimbabwe |
| publisher |
Centers for Disease Control and Prevention |
| publishDate |
2021 |
| url |
https://doaj.org/article/f0017e9d5d4941b1826503127913b7fc |
| work_keys_str_mv |
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